YfjR

• Description: similar to 3-hydroxyisobutyrate dehydrogenase
  
  

Gene name	yfjR
Synonyms
Essential	no
Product	3-hydroxyisobutyrate dehydrogenase
Function	unknown
Gene expression levels in SubtiExpress: yfjR
MW, pI	27 kDa, 4.782
Gene length, protein length	783 bp, 261 aa
Immediate neighbours	pdaA, yfjQ
Sequences	Protein DNA DNA_with_flanks
Genetic context This image was kindly provided by SubtiList
Expression at a glance   PubMed

Categories containing this gene/protein

phosphoproteins, poorly characterized/ putative enzymes

This gene is a member of the following regulons

YclJ regulon

The gene

Basic information

• Locus tag: BSU07990

Database entries

• DBTBS entry: [1]

• SubtiList entry: [2]

The protein

Basic information/ Evolution

• Catalyzed reaction/ biological activity:

• Protein family: 3-hydroxyisobutyrate dehydrogenase family (according to Swiss-Prot)

• Paralogous protein(s): YkwC

Extended information on the protein

• Kinetic information:

• Domains:

• Modification: phosphorylated on ser/ thr/ tyr PubMed

• Cofactor(s):

• Effectors of protein activity:

• Interactions:

• Localization:

Database entries

• Structure:

• UniProt: O34969

• KEGG entry: [3]

• E.C. number:

Expression and regulation

• Operon: yfjR (according to DBTBS)

• Expression browser: yfjR PubMed

• Sigma factor:

• Regulation:

• Regulatory mechanism:
  • YclJ: transcription activation PubMed

• Additional information:

Biological materials

• Mutant:

• Expression vector:

• lacZ fusion:

• GFP fusion:

• two-hybrid system:

• Antibody:

References

Mitsuo Ogura, Kensuke Tsukahara, Teruo Tanaka
Identification of the sequences recognized by the Bacillus subtilis response regulator YclJ.
Arch Microbiol: 2010, 192(7);569-80
[PubMed:20512483] [WorldCat.org] [DOI] (I p)

Alain Lévine, Françoise Vannier, Cédric Absalon, Lauriane Kuhn, Peter Jackson, Elaine Scrivener, Valérie Labas, Joëlle Vinh, Patrick Courtney, Jérôme Garin, Simone J Séror
Analysis of the dynamic Bacillus subtilis Ser/Thr/Tyr phosphoproteome implicated in a wide variety of cellular processes.
Proteomics: 2006, 6(7);2157-73
[PubMed:16493705] [WorldCat.org] [DOI] (P p)