VmlR

• Description: ABC transporter (ATP-binding protein), efflux of antibiotics (virginiamycin M, lincomycin)
  
  

Gene name	vmlR
Synonyms	expZ
Essential	no
Product	antibiotic efflux ABC transporter (ATP-binding protein)
Function	efflux of antibiotics (virginiamycin M, lincomycin)
Gene expression levels in SubtiExpress: vmlR
MW, pI	62 kDa, 6.727
Gene length, protein length	1641 bp, 547 aa
Immediate neighbours	ydgE, ydgF
Sequences	Protein DNA Advanced_DNA
Genetic context This image was kindly provided by SubtiList
Expression at a glance   PubMed

Categories containing this gene/protein

ABC transporters, resistance against toxins/ antibiotics

This gene is a member of the following regulons

RNA switch/ other

The gene

Basic information

• Locus tag: BSU05610

Database entries

• DBTBS entry: no entry

• SubtiList entry: [1]

The protein

Basic information/ Evolution

• Catalyzed reaction/ biological activity:

• Protein family: ABC transporter family (according to Swiss-Prot)

• Paralogous protein(s):

Extended information on the protein

• Kinetic information:

• Domains:

• Modification:

• Cofactor(s):

• Effectors of protein activity:

• Interactions:

• Localization:

Database entries

• Structure:

• UniProt: P39115

• KEGG entry: [2]

• E.C. number:

Expression and regulation

• Operon: vmlR PubMed

• Expression browser: vmlR PubMed

• Sigma factor: SigA PubMed

• Regulation: induced by virginiamycin M or lincomycin PubMed

• Regulatory mechanism: transcriptional antitermination, details are unknown PubMed

• Additional information:
  • A ncRNA is predicted between vmlR and ydgF PubMed

Biological materials

• Mutant:

• Expression vector:

• lacZ fusion:

• GFP fusion:

• two-hybrid system:

• Antibody: