NtdR

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Gene name ntdR
Synonyms yhjM
Essential no
Product transcriptional regulator (LacI family)
Function regulation of the ntdA-ntdB-ntdC-glcP operon
Gene expression levels in SubtiExpress: ntdR
MW, pI 37 kDa, 6.645
Gene length, protein length 987 bp, 329 aa
Immediate neighbours ntdA, yhjN
Sequences Protein DNA Advanced_DNA
Genetic context
YhjM context.gif
This image was kindly provided by SubtiList
Expression at a glance   PubMed
NtdR expression.png
























Categories containing this gene/protein

miscellaneous metabolic pathways, transcription factors and their control, biosynthesis of antibacterial compounds

This gene is a member of the following regulons

AbrB regulon

The NtdR regulon:

The gene

Basic information

  • Locus tag: BSU10560

Phenotypes of a mutant

Database entries

  • DBTBS entry: [1]
  • SubtiList entry: [2]

Additional information

The protein

Basic information/ Evolution

  • Paralogous protein(s):

Extended information on the protein

  • Kinetic information:
  • Domains:
  • Modification:
  • Cofactor(s):
  • Effectors of protein activity:

Database entries

  • Structure:
  • KEGG entry: [3]
  • E.C. number:

Additional information

Expression and regulation

  • Sigma factor:
  • Regulation:
  • Regulatory mechanism:
  • Additional information:

Biological materials

  • Mutant:
  • Expression vector:
  • lacZ fusion:
  • GFP fusion:
  • two-hybrid system:
  • Antibody:

Labs working on this gene/protein

Your additional remarks

References

Reviews

Takashi Inaoka, Kozo Ochi
Activation of dormant secondary metabolism neotrehalosadiamine synthesis by an RNA polymerase mutation in Bacillus subtilis.
Biosci Biotechnol Biochem: 2011, 75(4);618-23
[PubMed:21512256] [WorldCat.org] [DOI] (I p)

Original publications

Additional publications: PubMed

Takashi Inaoka, Kozo Ochi
Glucose uptake pathway-specific regulation of synthesis of neotrehalosadiamine, a novel autoinducer produced in Bacillus subtilis.
J Bacteriol: 2007, 189(1);65-75
[PubMed:17056753] [WorldCat.org] [DOI] (P p)

Takashi Inaoka, Kosaku Takahashi, Hiroshi Yada, Mitsuru Yoshida, Kozo Ochi
RNA polymerase mutation activates the production of a dormant antibiotic 3,3'-neotrehalosadiamine via an autoinduction mechanism in Bacillus subtilis.
J Biol Chem: 2004, 279(5);3885-92
[PubMed:14612444] [WorldCat.org] [DOI] (P p)