AlbA

• Description: radical S-adenosylmethionine enzyme, antilisterial bacteriocin (subtilosin) production
  
  

Gene name	albA
Synonyms	ywiA
Essential	no
Product	radical S-adenosylmethionine enzyme
Function	antilisterial bacteriocin (subtilosin) production
Gene expression levels in SubtiExpress: albA
MW, pI	51 kDa, 6.195
Gene length, protein length	1344 bp, 448 aa
Immediate neighbours	sboX, albB
Sequences	Protein DNA Advanced_DNA
Genetic context This image was kindly provided by SubtiList
Expression at a glance   PubMed

Categories containing this gene/protein

miscellaneous metabolic pathways, biosynthesis of antibacterial compounds

This gene is a member of the following regulons

AbrB regulon, ResD regulon, Rok regulon

The gene

Basic information

• Locus tag: BSU37370

Database entries

• DBTBS entry: [1]

• SubtiList entry: [2]

The protein

Basic information/ Evolution

• Catalyzed reaction/ biological activity:
  • catalyzes thioether bond formation in subtilosin A PubMed
• Protein family:

• Paralogous protein(s):

Extended information on the protein

• Kinetic information:

• Domains:

• Modification:

• Cofactor(s): contains two [4Fe-4S] clusters PubMed

• Effectors of protein activity:

• Interactions:

• Localization:

Database entries

• Structure:

• UniProt: P71011

• KEGG entry: [3]

• E.C. number:

Expression and regulation

• Operon: sboA-sboX-albA-albB-albC-albD-albE-albF-albG PubMed

• Expression browser: albA PubMed

• Sigma factor: SigA PubMed PubMed

• Regulation:
  • repressed by Rok PubMed
  • expressed under anaerobic conditions (ResD) PubMed
  • repressed during logrithmic growth (AbrB) PubMed

• Regulatory mechanism:
  • Rok: transcription repression PubMed
  • ResD: transcription activation PubMed
  • AbrB: transcription repression PubMed

• Additional information:

Biological materials

• Mutant:

• Expression vector:

• lacZ fusion:

• GFP fusion:

• two-hybrid system:

• Antibody:

References

Additional publications: PubMed