ComEB

• Description: late competence protein required for DNA binding and uptake
  
  

Gene name	comEB
Synonyms	comD
Essential	no
Product	late competence protein
Function	genetic compentence
Gene expression levels in SubtiExpress: comEB
Metabolic function and regulation of this protein in SubtiPathways: Nucleotides (regulation), Protein secretion
MW, pI	20 kDa, 5.368
Gene length, protein length	567 bp, 189 aa
Immediate neighbours	comEC, comEA
Sequences	Protein DNA Advanced_DNA
Genetic context This image was kindly provided by SubtiList
Expression at a glance   PubMed

Categories containing this gene/protein

genetic competence, membrane proteins

This gene is a member of the following regulons

ComK regulon, ComN regulon

The gene

Basic information

• Locus tag: BSU25580

Database entries

• DBTBS entry: [1]

• SubtiList entry: [2]

The protein

Basic information/ Evolution

• Catalyzed reaction/ biological activity:

• Protein family: cytidine and deoxycytidylate deaminase family (according to Swiss-Prot)

• Paralogous protein(s):

Extended information on the protein

• Kinetic information:

• Domains:

• Modification:

• Cofactor(s):

• Effectors of protein activity:

• Interactions:

• Localization:
  • cell membrane (according to Swiss-Prot)
  • localizes to one or both cell poles PubMed

Database entries

• Structure:

• UniProt: P32393

• KEGG entry: [3]

• E.C. number:

Expression and regulation

• Operon: comEA-comEB-comEC PubMed

• Expression browser: comEB PubMed

• Sigma factor: SigA PubMed

• Regulation:

• Regulatory mechanism:
  • post-translational control by ComN PubMed
  • yutB is required for transcription PubMed
  • ComK: transcription activation PubMed

• Additional information:

Biological materials

• Mutant:

• Expression vector:

• lacZ fusion:

• GFP fusion:

• two-hybrid system:

• Antibody: