KdgT

• Description: 2-keto-3-deoxygluconate permease
  
  

Gene name	kdgT
Synonyms
Essential	no
Product	2-keto-3-deoxygluconate permease
Function	utilization of galacturonic acid
Gene expression levels in SubtiExpress: kdgT
MW, pI	34 kDa, 8.935
Gene length, protein length	990 bp, 330 aa
Immediate neighbours	ypwA, kdgA
Get the DNA and protein sequences (Barbe et al., 2009)
Genetic context This image was kindly provided by SubtiList
Expression at a glance   PubMed

Categories containing this gene/protein

transporters/ other, utilization of specific carbon sources

This gene is a member of the following regulons

CcpA regulon, KdgR regulon, Efp-dependent proteins

The gene

Basic information

• Locus tag: BSU22090

Database entries

• DBTBS entry: [1]

• SubtiList entry: [2]

The protein

Basic information/ Evolution

• Catalyzed reaction/ biological activity:

• Protein family: sigma-70 factor family (according to Swiss-Prot)

• Paralogous protein(s):

Extended information on the protein

• Kinetic information:

• Domains:

• Modification:

• Cofactor(s):

• Effectors of protein activity:

• Interactions:

• Localization:

Database entries

• Structure:

• UniProt: P50847

• KEGG entry: [3]

• E.C. number:

Expression and regulation

• Operon: kdgR-kdgK-kdgA-kdgT PubMed

• Expression browser: kdgT PubMed

• Sigma factor: SigA PubMed

• Regulation:
  • induced by galacturonate (KdgR) PubMed
  • repressed by glucose (CcpA) PubMed

• Regulatory mechanism:
  • KdgR: transcription repression PubMed
  • CcpA: transcription repression PubMed

• Additional information:
  • translation is likely to require Efp due to the presence of several consecutive proline residues PubMed

Biological materials

• Mutant:

• Expression vector:

• lacZ fusion:

• GFP fusion:

• two-hybrid system:

• Antibody:

References

Petar Pujic, Rozenn Dervyn, Alexei Sorokin, S Dusko Ehrlich
The kdgRKAT operon of Bacillus subtilis: detection of the transcript and regulation by the kdgR and ccpA genes.
Microbiology (Reading): 1998, 144 ( Pt 11);3111-3118
[PubMed:9846747] [WorldCat.org] [DOI] (P p)