ComFC

• Description: late competence gene
  
  

Gene name	comFC
Synonyms
Essential	no
Product	unknown
Function	compentence
Gene expression levels in SubtiExpress: comFC
MW, pI	26 kDa, 8.851
Gene length, protein length	687 bp, 229 aa
Immediate neighbours	yvyF, comFB
Get the DNA and protein sequences (Barbe et al., 2009)
Genetic context This image was kindly provided by SubtiList
Expression at a glance   PubMed

Categories containing this gene/protein

genetic competence, phosphoproteins

This gene is a member of the following regulons

ComK regulon

The gene

Basic information

• Locus tag: BSU35450

Database entries

• DBTBS entry: [1]

• SubtiList entry: [2]

The protein

Basic information/ Evolution

• Catalyzed reaction/ biological activity:

• Protein family: comF/gntX family (according to Swiss-Prot)

• Paralogous protein(s):

Extended information on the protein

• Kinetic information:

• Domains:

• Modification:
  • phosphorylated on Arg-74 PubMed

• Cofactor(s):

• Effectors of protein activity:

• Interactions:

• Localization:
  • localizes to one or both cell poles PubMed

Database entries

• Structure:

• UniProt: P39147

• KEGG entry: [3]

• E.C. number:

Expression and regulation

• Operon: comFA-comFB-comFC-yvyF-flgM-yvyG-flgK-flgL PubMed

• Expression browser: comFC PubMed

• Sigma factor: comFA: SigA PubMed

• Regulation:

• Regulatory mechanism:
  • ComK: transcription activation PubMed

• Additional information:

Biological materials

• Mutant:

• Expression vector: for expression, purification in E. coli with N-terminal His-tag, pRSETA available in Gerth lab

• lacZ fusion:

• GFP fusion:

• two-hybrid system:

• Antibody: