NudF

From SubtiWiki
Revision as of 07:49, 20 April 2012 by 134.76.70.252 (talk)
Jump to: navigation, search
  • Description: involved in isopentenol (isoprenoid) biosynthesis

Gene name nudF
Synonyms yqkG
Essential no
Product unknown
Function isoprenoid biosynthesis
MW, pI 20 kDa, 4.586
Gene length, protein length 555 bp, 185 aa
Immediate neighbours yqxK, mciZ
Get the DNA and protein sequences
(Barbe et al., 2009)
Genetic context
NudF context.gif
This image was kindly provided by SubtiList
Expression at a glance   PubMed
NudF expression.png
























Categories containing this gene/protein

biosynthesis of lipids

This gene is a member of the following regulons

The gene

Basic information

  • Locus tag: BSU23610

Phenotypes of a mutant

Database entries

  • DBTBS entry: no entry
  • SubtiList entry: [1]

Additional information

The protein

Basic information/ Evolution

  • Catalyzed reaction/ biological activity: ADP-ribose + H2O = AMP + D-ribose 5-phosphate (according to Swiss-Prot)
  • Paralogous protein(s):

Extended information on the protein

  • Kinetic information:
  • Domains:
  • Modification:
  • Cofactor(s):
  • Effectors of protein activity:

Database entries

  • Structure:
  • KEGG entry: [2]

Additional information

Expression and regulation

  • Operon:
  • Sigma factor:
  • Regulation:
  • Regulatory mechanism:
  • Additional information:

Biological materials

  • Mutant:
  • Expression vector:
  • lacZ fusion:
  • GFP fusion:
  • two-hybrid system:
  • Antibody:

Labs working on this gene/protein

Your additional remarks

References

Sydnor T Withers, Shayin S Gottlieb, Bonny Lieu, Jack D Newman, Jay D Keasling
Identification of isopentenol biosynthetic genes from Bacillus subtilis by a screening method based on isoprenoid precursor toxicity.
Appl Environ Microbiol: 2007, 73(19);6277-83
[PubMed:17693564] [WorldCat.org] [DOI] (P p)

C A Dunn, S F O'Handley, D N Frick, M J Bessman
Studies on the ADP-ribose pyrophosphatase subfamily of the nudix hydrolases and tentative identification of trgB, a gene associated with tellurite resistance.
J Biol Chem: 1999, 274(45);32318-24
[PubMed:10542272] [WorldCat.org] [DOI] (P p)