ThiU

• Description: thiamine ABC transporter (binding protein)
  
  

Gene name	thiU
Synonyms	ykoF
Essential	no
Product	thiamine ABC transporter (binding protein)
Function	thiamine uptake
Interactions involving this protein in SubtInteract: ThiU
Metabolic function and regulation of this protein in SubtiPathways: Thiamin
MW, pI	21 kDa, 6.046
Gene length, protein length	600 bp, 200 aa
Immediate neighbours	thiV, ykoG
Get the DNA and protein sequences (Barbe et al., 2009)
Genetic context This image was kindly provided by SubtiList

Categories containing this gene/protein

ABC transporters, biosynthesis of cofactors, membrane proteins

This gene is a member of the following regulons

Thi-box

The gene

Basic information

• Locus tag: BSU13240

Expression

Database entries

• DBTBS entry: no entry

• SubtiList entry: [1]

The protein

Basic information/ Evolution

• Catalyzed reaction/ biological activity:

• Protein family:

• Paralogous protein(s):

Extended information on the protein

• Kinetic information:

• Domains:

• Modification:

• Cofactor(s):

• Effectors of protein activity:

• Interactions:
  • ThiW-(ThiV-ThiX)-ThiU PubMed

• Localization: membrane associated (via ThiV-ThiX) PubMed

Database entries

• Structure: 1SBR (complex with thiamine), 1S99

• UniProt: O34911

• KEGG entry: [2]

• E.C. number:

Expression and regulation

• Operon: thiU-thiV-thiW-thiX PubMed

• Sigma factor:

• Regulation:
  • repressed by thiamine (Thi-box) PubMed

• Regulatory mechanism:
  • Thi-box: RNA switch PubMed

• Additional information:

Biological materials

• Mutant:

• Expression vector:

• lacZ fusion:

• GFP fusion:

• two-hybrid system:

• Antibody: