FlgL

• Description: flagellar hook-associated protein 3 (HAP3)
  
  

Gene name	flgL
Synonyms	yviD
Essential	no
Product	flagellar hook-associated protein 3 (HAP3)
Function	movement and chemotaxis
MW, pI	32 kDa, 4.42
Gene length, protein length	894 bp, 298 aa
Immediate neighbours	yviE, flgK
Get the DNA and protein sequences (Barbe et al., 2009)
Genetic context This image was kindly provided by SubtiList

Categories containing this gene/protein

motility and chemotaxis

This gene is a member of the following regulons

ComK regulon, DegU regulon, SigD regulon

The gene

Basic information

• Locus tag: BSU35400

Database entries

• DBTBS entry: [1]

• SubtiList entry: [2]

The protein

Basic information/ Evolution

• Catalyzed reaction/ biological activity:

• Protein family: bacterial flagellin family (according to Swiss-Prot)

• Paralogous protein(s):

Extended information on the protein

• Kinetic information:

• Domains:

• Modification:

• Cofactor(s):

• Effectors of protein activity:

• Interactions:

• Localization: secreted (according to Swiss-Prot)

Database entries

• Structure:

• UniProt: P96501

• KEGG entry: [3]

• E.C. number:

Expression and regulation

• Operon:
  • comFA-comFB-comFC-yvyF-flgM-yvyG-flgK-flgL PubMed
  • yvyF-flgM-yvyG-flgK-flgL PubMed
  • flgM-yvyG-flgK-flgL PubMed

• Sigma factor:
  • comFA: SigA PubMed
  • yvyF: SigD PubMed
  • flgM: SigD PubMed

• Regulation:

• Regulatory mechanism:
  • ComK: transcription activation PubMed
  • flgM: DegU-P: transcription activation PubMed

• Additional information:

Biological materials

• Mutant:

• Expression vector:

• lacZ fusion:

• GFP fusion:

• two-hybrid system:

• Antibody:

References

Additional publications: PubMed

D B Mirel, P Lauer, M J Chamberlin
Identification of flagellar synthesis regulatory and structural genes in a sigma D-dependent operon of Bacillus subtilis.
J Bacteriol: 1994, 176(15);4492-500
[PubMed:8045879] [WorldCat.org] [DOI] (P p)

J A Londoño-Vallejo, D Dubnau
comF, a Bacillus subtilis late competence locus, encodes a protein similar to ATP-dependent RNA/DNA helicases.
Mol Microbiol: 1993, 9(1);119-31
[PubMed:8412657] [WorldCat.org] [DOI] (P p)