SpoIIIC

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Gene name spoIIIC
Synonyms sigK, spoIVD, spoIVE
Essential no
Product RNA polymerase sporulation-specific sigma factor
(SigK) (C-terminal half)
Function late mother cell-specific gene expression
Interactions involving this protein in SubtInteract: SpoIIIC
MW, pI 16 kDa, 9.608
Gene length, protein length 414 bp, 138 aa
Immediate neighbours yqaB, yrkS
Gene sequence (+200bp) Protein sequence
Genetic context
SpoIIIC context.gif
This image was kindly provided by SubtiList




Categories containing this gene/protein

transcription, sigma factors and their control, sporulation proteins, membrane proteins

This gene is a member of the following regulons

GerE regulon, SigE regulon, SigK regulon, SpoIIID regulon

The SigK regulon

The gene

Basic information

  • Locus tag: BSU26390

Phenotypes of a mutant

Database entries

  • DBTBS entry: [1]
  • SubtiList entry: [2]

Additional information

The protein

Basic information/ Evolution

  • Catalyzed reaction/ biological activity:
  • Protein family:
  • Paralogous protein(s):

Extended information on the protein

  • Kinetic information:
  • Domains:
  • Modification:
  • Cofactor(s):
  • Effectors of protein activity:
  • Localization:

Database entries

  • Structure:
  • KEGG entry: [3]
  • E.C. number:

Additional information

Expression and regulation

  • Additional information:
    • SigK is activated by processing of membrane-bound pro-SigK by the SpoIVFB metalloprotease PubMed
    • spoIVCB and spoIIIC form a composite gene in the mother cell during sporulation by excising the intervening DNA sequence.

Biological materials

  • Mutant:
  • Expression vector:
  • lacZ fusion:
  • GFP fusion:
  • two-hybrid system:
  • Antibody:

Labs working on this gene/protein

Your additional remarks

References

The SigK regulon

Other original publications