PdeH

• Description: unknown
  
  

Gene name	yuxH
Synonyms	comB, yufA
Essential	no
Product	unknown
Function	unknown
MW, pI	47 kDa, 5.36
Gene length, protein length	1227 bp, 409 aa
Immediate neighbours	yuzC, pncB
Get the DNA and protein sequences (Barbe et al., 2009)
Genetic context This image was kindly provided by SubtiList

The gene

Basic information

• Locus tag: BSU31740

Database entries

• DBTBS entry: [1]

• SubtiList entry: [2]

Categories containing this gene/protein

proteins of unknown function

The protein

Basic information/ Evolution

• Catalyzed reaction/ biological activity: (2R)-2-phospho-3-sulfolactate + H₂O = (2R)-3-sulfolactate + phosphate (according to Swiss-Prot)

• Protein family: comB family (according to Swiss-Prot)

• Paralogous protein(s):

Extended information on the protein

• Kinetic information:

• Domains:

• Modification:

• Cofactor(s):

• Effectors of protein activity:

• Interactions:

• Localization:

Database entries

• Structure:

• UniProt: P14203

• KEGG entry: [3]

• E.C. number: 3.1.3.71

Expression and regulation

• Operon: yuxH PubMed

• Sigma factor: SigA PubMed

• Regulation:
  • repressed under conditions that trigger sporulation (Spo0A) PubMed

• Regulatory mechanism:
  • Spo0A: transcription repression PubMed

• Additional information:

Biological materials

• Mutant:

• Expression vector:

• lacZ fusion:

• GFP fusion:

• two-hybrid system:

• Antibody:

References

Masaya Fujita, José Eduardo González-Pastor, Richard Losick
High- and low-threshold genes in the Spo0A regulon of Bacillus subtilis.
J Bacteriol: 2005, 187(4);1357-68
[PubMed:15687200] [WorldCat.org] [DOI] (P p)

Virginie Molle, Masaya Fujita, Shane T Jensen, Patrick Eichenberger, José E González-Pastor, Jun S Liu, Richard Losick
The Spo0A regulon of Bacillus subtilis.
Mol Microbiol: 2003, 50(5);1683-701
[PubMed:14651647] [WorldCat.org] [DOI] (P p)

Y Weinrauch, N Guillen, D A Dubnau
Sequence and transcription mapping of Bacillus subtilis competence genes comB and comA, one of which is related to a family of bacterial regulatory determinants.
J Bacteriol: 1989, 171(10);5362-75
[PubMed:2507523] [WorldCat.org] [DOI] (P p)