SsuC

• Description: aliphatic sulfonate ABC transporter (permease)
  
  

Gene name	ssuC
Synonyms	ygaM, yzeB
Essential	no
Product	aliphatic sulfonate ABC transporter (permease)
Function	sulfonate uptake
Metabolic function and regulation of this protein in SubtiPathways: Cys, Met & Sulfate assimilation
MW, pI	30 kDa, 10.481
Gene length, protein length	828 bp, 276 aa
Immediate neighbours	ssuA, ssuD
Get the DNA and protein sequences (Barbe et al., 2009)
Genetic context This image was kindly provided by SubtiList

The gene

Basic information

• Locus tag: BSU08850

Database entries

• DBTBS entry: no entry

• SubtiList entry: [1]

The protein

Basic information/ Evolution

• Catalyzed reaction/ biological activity:

• Protein family: ABC transmembrane type-1 domain (according to Swiss-Prot)

• Paralogous protein(s):

Extended information on the protein

• Kinetic information:

• Domains:

• Modification:

• Cofactor(s):

• Effectors of protein activity:

• Interactions:

• Localization: cell membrane (according to Swiss-Prot)

Database entries

• Structure:

• UniProt: P40401

• KEGG entry: [2]

• E.C. number:

Expression and regulation

• Operon: ssuB-ssuA-ssuC-ssuD-ygaN

• Sigma factor: SigA

• Regulation: repressed in the presence of cysteine (CymR) PubMed
  • repressed in the presence of cysteine (CymR) PubMed

• Regulatory mechanism: CymR: transcription repression PubMed
  • CymR: transcription repression PubMed

• Additional information:

Biological materials

• Mutant:

• Expression vector:

• lacZ fusion:

• GFP fusion:

• two-hybrid system:

• Antibody:

References

Sergine Even, Pierre Burguière, Sandrine Auger, Olga Soutourina, Antoine Danchin, Isabelle Martin-Verstraete
Global control of cysteine metabolism by CymR in Bacillus subtilis.
J Bacteriol: 2006, 188(6);2184-97
[PubMed:16513748] [WorldCat.org] [DOI] (P p)

Kyle N Erwin, Shunji Nakano, Peter Zuber
Sulfate-dependent repression of genes that function in organosulfur metabolism in Bacillus subtilis requires Spx.
J Bacteriol: 2005, 187(12);4042-9
[PubMed:15937167] [WorldCat.org] [DOI] (P p)

Y Quentin, G Fichant, F Denizot
Inventory, assembly and analysis of Bacillus subtilis ABC transport systems.
J Mol Biol: 1999, 287(3);467-84
[PubMed:10092453] [WorldCat.org] [DOI] (P p)

Jan R van der Ploeg, Nicola J Cummings, Thomas Leisinger, Ian F Connerton
Bacillus subtilis genes for the utilization of sulfur from aliphatic sulfonates.
Microbiology (Reading): 1998, 144 ( Pt 9);2555-2561
[PubMed:9782504] [WorldCat.org] [DOI] (P p)