Difference between revisions of "Sandbox"

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Line 1: Line 1:
−
* '''Description:''' maltodextrin ABC transporter, binding protein <br/><br/>
+
* '''Description:''' UDP-N-acetylglucosamine 2-epimerase <br/><br/>
  
 
{| align="right" border="1" cellpadding="2"  
 
{| align="right" border="1" cellpadding="2"  
 
|-
 
|-
 
|style="background:#ABCDEF;" align="center"|'''Gene name'''
 
|style="background:#ABCDEF;" align="center"|'''Gene name'''
−
|''mdxE''
+
|''mnaA''
 
|-
 
|-
−
|style="background:#ABCDEF;" align="center"| '''Synonyms''' || ''yvdG ''
+
|style="background:#ABCDEF;" align="center"| '''Synonyms''' || ''yvyH ''
 
|-
 
|-
−
|style="background:#ABCDEF;" align="center"| '''Essential''' || no
+
|style="background:#ABCDEF;" align="center"| '''Essential''' || yes [http://www.ncbi.nlm.nih.gov/pubmed/12682299 PubMed]
 
|-
 
|-
−
|style="background:#ABCDEF;" align="center"| '''Product''' || maltodextrin ABC transporter, binding protein
+
|style="background:#ABCDEF;" align="center"| '''Product''' || UDP-N-acetylglucosamine 2-epimerase
 
|-
 
|-
−
|style="background:#ABCDEF;" align="center"|'''Function''' || maltodextrin utilization
+
|style="background:#ABCDEF;" align="center"|'''Function''' || biosynthesis of teichoic acid
 
|-
 
|-
−
|style="background:#ABCDEF;" align="center"| '''MW, pI''' || 45 kDa, 4.911  
+
|style="background:#ABCDEF;" align="center"| '''MW, pI''' || 42 kDa, 5.469  
 
|-
 
|-
−
|style="background:#ABCDEF;" align="center"| '''Gene length, protein length''' || 1251 bp, 417 aa  
+
|style="background:#ABCDEF;" align="center"| '''Gene length, protein length''' || 1140 bp, 380 aa  
 
|-
 
|-
−
|style="background:#ABCDEF;" align="center"|'''Immediate neighbours''' || ''[[mdxF]]'', ''[[yvdF]]''
+
|style="background:#ABCDEF;" align="center"|'''Immediate neighbours''' || ''[[lytR]]'', ''[[gtaB]]''
 
|-
 
|-
−
|colspan="2" style="background:#FAF8CC;" align="center"|'''Get the DNA and protein [http://srs.ebi.ac.uk/srsbin/cgi-bin/wgetz?-e+&#91;EMBLCDS:CAB15466&#93;+-newId sequences] <br/> (Barbe ''et al.'', 2009)'''
+
|colspan="2" style="background:#FAF8CC;" align="center"|'''Get the DNA and protein [http://srs.ebi.ac.uk/srsbin/cgi-bin/wgetz?-e+&#91;EMBLCDS:CAB15583&#93;+-newId sequences] <br/> (Barbe ''et al.'', 2009)'''
 
|-
 
|-
−
|colspan="2" | '''Genetic context''' <br/> [[Image:yvdG_context.gif]]
+
|colspan="2" | '''Genetic context''' <br/> [[Image:yvyH_context.gif]]
 
  <div align="right"> <small>This image was kindly provided by [http://genolist.pasteur.fr/SubtiList/ SubtiList]</small></div>
 
  <div align="right"> <small>This image was kindly provided by [http://genolist.pasteur.fr/SubtiList/ SubtiList]</small></div>
 
|-
 
|-
Line 35: Line 35:
 
=== Basic information ===
 
=== Basic information ===
  
−
* '''Locus tag:''' BSU34610
+
* '''Locus tag:''' BSU35660
  
 
===Phenotypes of a mutant ===
 
===Phenotypes of a mutant ===
 +
 +
essential [http://www.ncbi.nlm.nih.gov/pubmed/12682299 PubMed]
  
 
=== Database entries ===
 
=== Database entries ===
Line 43: Line 45:
 
* '''DBTBS entry:''' no entry
 
* '''DBTBS entry:''' no entry
  
−
* '''SubtiList entry:''' [http://genolist.pasteur.fr/SubtiList/genome.cgi?gene_detail+BG12416]
+
* '''SubtiList entry:''' [http://genolist.pasteur.fr/SubtiList/genome.cgi?gene_detail+BG10403]
  
 
=== Additional information===
 
=== Additional information===
Line 52: Line 54:
 
=== Basic information/ Evolution ===
 
=== Basic information/ Evolution ===
  
−
* '''Catalyzed reaction/ biological activity:'''  
+
* '''Catalyzed reaction/ biological activity:''' UDP-N-acetyl-D-glucosamine = UDP-N-acetyl-D-mannosamine (according to Swiss-Prot)
  
−
* '''Protein family:''' bacterial solute-binding protein 1 family (according to Swiss-Prot)
+
* '''Protein family:''' UDP-N-acetylglucosamine 2-epimerase family (according to Swiss-Prot)
  
−
* '''Paralogous protein(s):''' [[CycB]]
+
* '''Paralogous protein(s):'''
  
 
=== Extended information on the protein ===
 
=== Extended information on the protein ===
Line 72: Line 74:
 
* '''Interactions:'''
 
* '''Interactions:'''
  
−
* '''Localization:''' cell membrane (according to Swiss-Prot)
+
* '''Localization:''' cytoplasm (according to Swiss-Prot)
  
 
=== Database entries ===
 
=== Database entries ===
  
−
* '''Structure:'''
+
* '''Structure:''' [http://www.rcsb.org/pdb/explore.do?structureId=1O6C 1O6C]
  
−
* '''Swiss prot entry:''' [http://www.uniprot.org/uniprot/O06989 O06989]
+
* '''Swiss prot entry:''' [http://www.uniprot.org/uniprot/P39131 P39131]
  
−
* '''KEGG entry:''' [http://www.genome.jp/dbget-bin/www_bget?bsu+BSU34610]
+
* '''KEGG entry:''' [http://www.genome.jp/dbget-bin/www_bget?bsu+BSU35660]
  
−
* '''E.C. number:'''
+
* '''E.C. number:''' [http://www.expasy.org/enzyme/5.1.3.14 5.1.3.14]
  
 
=== Additional information===
 
=== Additional information===

Revision as of 17:59, 7 June 2009

  • Description: UDP-N-acetylglucosamine 2-epimerase

Gene name mnaA
Synonyms yvyH
Essential yes PubMed
Product UDP-N-acetylglucosamine 2-epimerase
Function biosynthesis of teichoic acid
MW, pI 42 kDa, 5.469
Gene length, protein length 1140 bp, 380 aa
Immediate neighbours lytR, gtaB
Get the DNA and protein sequences
(Barbe et al., 2009)
Genetic context
YvyH context.gif
This image was kindly provided by SubtiList



The gene

Basic information

  • Locus tag: BSU35660

Phenotypes of a mutant

essential PubMed

Database entries

  • DBTBS entry: no entry
  • SubtiList entry: [1]

Additional information

The protein

Basic information/ Evolution

  • Catalyzed reaction/ biological activity: UDP-N-acetyl-D-glucosamine = UDP-N-acetyl-D-mannosamine (according to Swiss-Prot)
  • Protein family: UDP-N-acetylglucosamine 2-epimerase family (according to Swiss-Prot)
  • Paralogous protein(s):

Extended information on the protein

  • Kinetic information:
  • Domains:
  • Modification:
  • Cofactor(s):
  • Effectors of protein activity:
  • Interactions:
  • Localization: cytoplasm (according to Swiss-Prot)

Database entries

  • KEGG entry: [2]

Additional information

Expression and regulation

  • Operon:
  • Regulation:
  • Regulatory mechanism:
  • Additional information:

Biological materials

  • Mutant:
  • Expression vector:
  • lacZ fusion:
  • GFP fusion:
  • two-hybrid system:
  • Antibody:

Labs working on this gene/protein

Your additional remarks

References

  1. Author1, Author2 & Author3 (year) Title Journal volume: page-page. PubMed
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