Difference between revisions of "ArgH"

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=== Basic information ===
 
=== Basic information ===
  
* '''Locus tag:'''
+
* '''Locus tag:''' BSU29440
  
 
===Phenotypes of a mutant ===
 
===Phenotypes of a mutant ===
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* '''Swiss prot entry:''' [http://www.uniprot.org/uniprot/O34858 O34858]
 
* '''Swiss prot entry:''' [http://www.uniprot.org/uniprot/O34858 O34858]
  
* '''KEGG entry:''' [http://www.genome.jp/dbget-bin/www_bget?bsu+BSU29440 BSU29440]
+
* '''KEGG entry:''' [http://www.genome.jp/dbget-bin/www_bget?bsu+BSU29440]
  
 
* '''E.C. number:''' [http://www.expasy.org/enzyme/4.3.2.1 4.3.2.1]
 
* '''E.C. number:''' [http://www.expasy.org/enzyme/4.3.2.1 4.3.2.1]

Revision as of 11:20, 3 June 2009

  • Description: argininosuccinate lyase

Gene name argH
Synonyms
Essential no
Product argininosuccinate lyase
Function biosynthesis of arginine
MW, pI 51 kDa, 4.859
Gene length, protein length 1383 bp, 461 aa
Immediate neighbours ytzD, argG
Get the DNA and protein sequences
(Barbe et al., 2009)
Genetic context
ArgH context.gif
This image was kindly provided by SubtiList



The gene

Basic information

  • Locus tag: BSU29440

Phenotypes of a mutant

Database entries

  • DBTBS entry: no entry
  • SubtiList entry: [1]

Additional information

The protein

Basic information/ Evolution

  • Catalyzed reaction/ biological activity: 2-(N(omega)-L-arginino)succinate = fumarate + L-arginine (according to Swiss-Prot)
  • Protein family: Argininosuccinate lyase subfamily (according to Swiss-Prot)
  • Paralogous protein(s):

Extended information on the protein

  • Kinetic information:
  • Domains:
  • Modification:
  • Cofactor(s):
  • Effectors of protein activity:
  • Interactions:
  • Localization: cytoplasm (according to Swiss-Prot)

Database entries

  • Structure:
  • KEGG entry: [2]

Additional information

Expression and regulation

  • Regulation: repressed by casamino acids PubMed, repressed by arginine (AhrC)
  • Regulatory mechanism: AhrC: transcription repression
  • Additional information:

Biological materials

  • Mutant:
  • Expression vector:
  • lacZ fusion:
  • GFP fusion:
  • two-hybrid system:
  • Antibody:

Labs working on this gene/protein

Your additional remarks

References

  1. Mäder et al. (2002) Transcriptome and Proteome Analysis of Bacillus subtilis Gene Expression Modulated by Amino Acid Availability. J. Bacteriol 184: 1844288-4295 PubMed
  2. Author1, Author2 & Author3 (year) Title Journal volume: page-page. PubMed