Difference between revisions of "LcfA"

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=Expression and regulation=
 
=Expression and regulation=
  
* '''Operon:'''  
+
* '''Operon:''' ''[[lcfA]]-[[fadR]]-[[fadB]]-[[etfB]]-[[etfA]]'' [http://www.ncbi.nlm.nih.gov/sites/entrez/17189250 PubMed]
  
 
* '''[[Sigma factor]]:'''  
 
* '''[[Sigma factor]]:'''  
  
* '''Regulation:''' repressed by glucose ([[CcpA]])   
+
* '''Regulation:''' repressed by glucose ([[CcpA]]), induced by long chain acyl-CoA (C14 ... C20) ([[FadR]]) [http://www.ncbi.nlm.nih.gov/sites/entrez/17189250 PubMed]  
 +
 
 +
* '''Regulatory mechanism:''' [[CcpA]]: transcription repression, [[FadR]]: transcription repression [http://www.ncbi.nlm.nih.gov/sites/entrez/17189250 PubMed]
  
* '''Regulatory mechanism:''' [[CcpA]]: transcription repression
 
  
 
* '''Additional information:'''  
 
* '''Additional information:'''  
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=Labs working on this gene/protein=
 
=Labs working on this gene/protein=
 +
  
 
=Your additional remarks=
 
=Your additional remarks=

Revision as of 11:27, 6 May 2009

  • Description: long chain acyl-CoA synthetase

Gene name lcfA
Synonyms
Essential no
Product long chain acyl-CoA synthetase
Function fatty acid degradation
MW, pI 62 kDa, 6.119
Gene length, protein length 1680 bp, 560 aa
Immediate neighbours fadR, yshE
Get the DNA and protein sequences
(Barbe et al., 2009)
Genetic context
LcfA context.gif
This image was kindly provided by SubtiList



The gene

Basic information

  • Coordinates:

Phenotypes of a mutant

Database entries

  • DBTBS entry: [1]
  • SubtiList entry: [2]

Additional information

The protein

Basic information/ Evolution

  • Catalyzed reaction/ biological activity:
  • Protein family:
  • Paralogous protein(s):

Extended information on the protein

  • Kinetic information:
  • Domains:
  • Modification:
  • Cofactor(s):
  • Effectors of protein activity:
  • Interactions:
  • Localization: cytoplasm (according to Swiss-Prot)

Database entries

  • Structure:
  • KEGG entry: [3]
  • E.C. number:

Additional information

Expression and regulation

  • Regulation: repressed by glucose (CcpA), induced by long chain acyl-CoA (C14 ... C20) (FadR) PubMed
  • Regulatory mechanism: CcpA: transcription repression, FadR: transcription repression PubMed


  • Additional information:

Biological materials

  • Mutant:
  • Expression vector:
  • lacZ fusion:
  • GFP fusion:
  • two-hybrid system:
  • Antibody:

Labs working on this gene/protein

Your additional remarks

References

  1. Author1, Author2 & Author3 (year) Title Journal volume: page-page. PubMed