Difference between revisions of "RsmG"
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= This gene is a member of the following [[regulons]] = | = This gene is a member of the following [[regulons]] = | ||
| − | {{SubtiWiki regulon|[[ComK regulon]]}} | + | {{SubtiWiki regulon|[[ComK regulon]]}}, |
| + | {{SubtiWiki regulon|[[DnaA regulon]]}} | ||
=The gene= | =The gene= | ||
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=== Additional information=== | === Additional information=== | ||
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=The protein= | =The protein= | ||
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* '''Expression browser:''' [http://genome.jouy.inra.fr/cgi-bin/seb/viewdetail.py?id=rsmG_4208870_4209589_-1 rsmG] {{PubMed|22383849}} | * '''Expression browser:''' [http://genome.jouy.inra.fr/cgi-bin/seb/viewdetail.py?id=rsmG_4208870_4209589_-1 rsmG] {{PubMed|22383849}} | ||
| − | * '''Sigma factor:''' | + | * '''[[Sigma factor]]:''' |
* '''Regulation:''' | * '''Regulation:''' | ||
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* '''Regulatory mechanism:''' | * '''Regulatory mechanism:''' | ||
** [[ComK]]: transcription activation {{PubMed|11948146}} | ** [[ComK]]: transcription activation {{PubMed|11948146}} | ||
| + | ** [[DnaA]]: transcription repression {{PubMed|26020636}} | ||
* '''Additional information:''' | * '''Additional information:''' | ||
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=References= | =References= | ||
| − | <pubmed>17573471 11948146 11807071</pubmed> | + | <pubmed>17573471 11948146 11807071 26020636</pubmed> |
[[Category:Protein-coding genes]] | [[Category:Protein-coding genes]] | ||
Revision as of 13:03, 1 June 2015
- Description: 7-methylguanosine methyltransferase specific for the 16S rRNA, glucose-inhibited division protein
| Gene name | gidB |
| Synonyms | |
| Essential | no |
| Product | 7-methylguanosine methyltransferase specific for the 16S rRNA |
| Function | rRNA modification |
| Gene expression levels in SubtiExpress: rsmG | |
| MW, pI | 26 kDa, 6.603 |
| Gene length, protein length | 717 bp, 239 aa |
| Immediate neighbours | noc, gidA |
| Sequences | Protein DNA DNA_with_flanks |
Genetic context 
This image was kindly provided by SubtiList
| |
Expression at a glance PubMed
| |
Contents
Categories containing this gene/protein
This gene is a member of the following regulons
The gene
Basic information
- Locus tag: BSU41000
Phenotypes of a mutant
low-level resistance to streptomycin, increased level of streptomycin-resistant rpsL mutants (200 times higher than in the wild type) PubMed
Database entries
- BsubCyc: BSU41000
- DBTBS entry: [1]
- SubtiList entry: [2]
Additional information
The protein
Basic information/ Evolution
- Catalyzed reaction/ biological activity: methylates the N7 position of nucleotide G535 in 16S rRNA PubMed
- Protein family: RNA methyltransferase rsmG family (according to Swiss-Prot)
- Paralogous protein(s):
Extended information on the protein
- Kinetic information:
- Domains:
- Modification:
- Cofactor(s):
- Effectors of protein activity:
- Localization: cytoplasm (according to Swiss-Prot)
Database entries
- BsubCyc: BSU41000
- Structure: 1XDZ
- UniProt: P25813
- KEGG entry: [3]
- E.C. number:
Additional information
Expression and regulation
- Regulation:
- Additional information:
- number of protein molecules per cell (minimal medium with glucose and ammonium): 156 PubMed
Biological materials
- Mutant:
- Expression vector:
- lacZ fusion:
- GFP fusion:
- two-hybrid system:
- Antibody:
Labs working on this gene/protein
Your additional remarks
References
Janet L Smith, Alan D Grossman
In Vitro Whole Genome DNA Binding Analysis of the Bacterial Replication Initiator and Transcription Factor DnaA.
PLoS Genet: 2015, 11(5);e1005258
[PubMed:26020636]
[WorldCat.org]
[DOI]
(I e)
Kenji Nishimura, Shanna K Johansen, Takashi Inaoka, Takeshi Hosaka, Shinji Tokuyama, Yasutaka Tahara, Susumu Okamoto, Fujio Kawamura, Stephen Douthwaite, Kozo Ochi
Identification of the RsmG methyltransferase target as 16S rRNA nucleotide G527 and characterization of Bacillus subtilis rsmG mutants.
J Bacteriol: 2007, 189(16);6068-73
[PubMed:17573471]
[WorldCat.org]
[DOI]
(P p)
Mitsuo Ogura, Hirotake Yamaguchi, Kazuo Kobayashi, Naotake Ogasawara, Yasutaro Fujita, Teruo Tanaka
Whole-genome analysis of genes regulated by the Bacillus subtilis competence transcription factor ComK.
J Bacteriol: 2002, 184(9);2344-51
[PubMed:11948146]
[WorldCat.org]
[DOI]
(P p)
Jörg Sievers, Brian Raether, Marta Perego, Jeff Errington
Characterization of the parB-like yyaA gene of Bacillus subtilis.
J Bacteriol: 2002, 184(4);1102-11
[PubMed:11807071]
[WorldCat.org]
[DOI]
(P p)
