Difference between revisions of "OppC"

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(References)
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= This gene is a member of the following [[regulons]] =
 
= This gene is a member of the following [[regulons]] =
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{{SubtiWiki regulon|[[CodY regulon]]}},
 
{{SubtiWiki regulon|[[ScoC regulon]]}},
 
{{SubtiWiki regulon|[[ScoC regulon]]}},
 
{{SubtiWiki regulon|[[TnrA regulon]]}}
 
{{SubtiWiki regulon|[[TnrA regulon]]}}
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=== Additional information===
 
=== Additional information===
 
 
 
  
 
=The protein=
 
=The protein=
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* '''Expression browser:''' [http://genome.jouy.inra.fr/cgi-bin/seb/viewdetail.py?id=oppC_1222533_1223450_1 oppC] {{PubMed|22383849}}
 
* '''Expression browser:''' [http://genome.jouy.inra.fr/cgi-bin/seb/viewdetail.py?id=oppC_1222533_1223450_1 oppC] {{PubMed|22383849}}
  
* '''Sigma factor:'''  
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* '''[[Sigma factor]]:'''  
  
 
* '''Regulation:'''  
 
* '''Regulation:'''  
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** [[TnrA]]: transcription activation [http://www.ncbi.nlm.nih.gov/sites/entrez/12823818 PubMed]
 
** [[TnrA]]: transcription activation [http://www.ncbi.nlm.nih.gov/sites/entrez/12823818 PubMed]
 
** [[ScoC]]: transcription repression [http://www.ncbi.nlm.nih.gov/sites/entrez/10383984 PubMed]
 
** [[ScoC]]: transcription repression [http://www.ncbi.nlm.nih.gov/sites/entrez/10383984 PubMed]
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** [[CodY]]: transcription repression, no derepression occurs, however, in a ''[[codY]]'' mutant, due to increased repression by [[ScoC]] {{PubMed|25966844}}
  
 
* '''Additional information:'''
 
* '''Additional information:'''
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=Biological materials =
 
=Biological materials =
  
* '''Mutant:''' BP68 (spc) available in [[Fabian Commichau]]'s lab
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* '''Mutant:'''  
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** BP68 (spc) available in [[Fabian Commichau]]'s lab
  
 
* '''Expression vector:'''
 
* '''Expression vector:'''
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=References=
 
=References=
<pubmed>12823818,1901616,10092453,9252573,21908671,12823818,10383984, 7997159 1899858</pubmed>
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<pubmed>12823818,1901616,10092453,9252573,21908671,12823818,10383984, 7997159 25966844 1899858</pubmed>
  
 
[[Category:Protein-coding genes]]
 
[[Category:Protein-coding genes]]

Revision as of 13:26, 15 May 2015

Gene name oppC
Synonyms spo0KC
Essential no
Product oligopeptide ABC transporter (permease)
Function initiation of sporulation, competence development
Gene expression levels in SubtiExpress: oppC
Interactions involving this protein in SubtInteract: OppC
Metabolic function and regulation of this protein in SubtiPathways:
oppC
MW, pI 33 kDa, 10.107
Gene length, protein length 915 bp, 305 aa
Immediate neighbours oppB, oppD
Sequences Protein DNA DNA_with_flanks
Genetic context
OppC context.gif
This image was kindly provided by SubtiList
Expression at a glance   PubMed
OppC expression.png















Categories containing this gene/protein

ABC transporters, utilization of nitrogen sources other than amino acids, genetic competence, phosphorelay, membrane proteins

This gene is a member of the following regulons

CodY regulon, ScoC regulon, TnrA regulon

The gene

Basic information

  • Locus tag: BSU11450

Phenotypes of a mutant

Database entries

  • DBTBS entry: no entry
  • SubtiList entry: [1]

Additional information

The protein

Basic information/ Evolution

  • Catalyzed reaction/ biological activity:
    • required for the uptake of quorum sensing peptides such as PhrH PubMed
  • Protein family: ABC transmembrane type-1 domain (according to Swiss-Prot)
  • Paralogous protein(s):

Extended information on the protein

  • Kinetic information:
  • Domains:
  • Modification:
  • Cofactor(s):
  • Effectors of protein activity:

Database entries

  • Structure:
  • KEGG entry: [2]
  • E.C. number:

Additional information

Expression and regulation

  • Regulation:
    • expressed in the absence of good nitrogen sources (glutamine or ammonium) (TnrA) PubMed
    • repressed during exponential growth (ScoC) PubMed
  • Regulatory mechanism:
    • TnrA: transcription activation PubMed
    • ScoC: transcription repression PubMed
    • CodY: transcription repression, no derepression occurs, however, in a codY mutant, due to increased repression by ScoC PubMed
  • Additional information:
    • number of protein molecules per cell (minimal medium with glucose and ammonium): 145 PubMed
    • number of protein molecules per cell (complex medium with amino acids, without glucose): 1155 PubMed

Biological materials

  • Expression vector:
  • lacZ fusion:
  • GFP fusion:
  • two-hybrid system:
  • Antibody:

Labs working on this gene/protein

Your additional remarks

References