Difference between revisions of "HemH"

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* '''Description:''' ferrochelatase <br/><br/>
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* '''Description:''' ferrochelatase, catalyzes the final step of heme b biosynthesis <br/><br/>
 
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=== Additional information===
 
=== Additional information===
 
 
 
  
 
=The protein=
 
=The protein=
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* '''Expression browser:''' [http://genome.jouy.inra.fr/cgi-bin/seb/viewdetail.py?id=hemH_1087250_1088182_1 hemH] {{PubMed|22383849}}
 
* '''Expression browser:''' [http://genome.jouy.inra.fr/cgi-bin/seb/viewdetail.py?id=hemH_1087250_1088182_1 hemH] {{PubMed|22383849}}
  
* '''Sigma factor:'''  
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* '''[[Sigma factor]]:'''  
  
 
* '''Regulation:'''  
 
* '''Regulation:'''  
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=References=
 
=References=
  
<pubmed>9384565,1459957,8119288, 21052751 23097001 16453119 </pubmed>
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<pubmed>9384565,1459957,8119288, 21052751 23097001 16453119 25826316</pubmed>
  
 
[[Category:Protein-coding genes]]
 
[[Category:Protein-coding genes]]

Revision as of 08:27, 1 April 2015

  • Description: ferrochelatase, catalyzes the final step of heme b biosynthesis

Gene name hemH
Synonyms hemF
Essential no
Product ferrochelatase
Function heme biosynthesis
Gene expression levels in SubtiExpress: hemH
Metabolic function and regulation of this protein in SubtiPathways:
HemH
MW, pI 35 kDa, 4.617
Gene length, protein length 930 bp, 310 aa
Immediate neighbours hemE, hemY
Sequences Protein DNA DNA_with_flanks
Genetic context
HemH context.gif
This image was kindly provided by SubtiList
Expression at a glance   PubMed
HemH expression.png















Categories containing this gene/protein

biosynthesis of cofactors

This gene is a member of the following regulons

The gene

Basic information

  • Locus tag: BSU10130

Phenotypes of a mutant

Database entries

  • DBTBS entry: [1]
  • SubtiList entry: [2]

Additional information

The protein

Basic information/ Evolution

  • Catalyzed reaction/ biological activity: insertion of Fe(2+) into protoporphyrin IX
  • Protein family: ferrochelatase family (according to Swiss-Prot)
  • Paralogous protein(s):

Extended information on the protein

  • Kinetic information:
  • Domains:
  • Modification:
  • Cofactor(s):
  • Effectors of protein activity:

Database entries

  • Structure: 2HK6 (complex with iron), 1AK1
  • KEGG entry: [3]
  • E.C. number:

Additional information

Expression and regulation

  • Regulation:
  • Regulatory mechanism:
  • Additional information:
    • number of protein molecules per cell (minimal medium with glucose and ammonium): 83 PubMed
    • number of protein molecules per cell (complex medium with amino acids, without glucose): 1426 PubMed
    • number of protein molecules per cell (minimal medium with glucose and ammonium, exponential phase): 1547 PubMed
    • number of protein molecules per cell (minimal medium with glucose and ammonium, early stationary phase after glucose exhaustion): 1289 PubMed
    • number of protein molecules per cell (minimal medium with glucose and ammonium, late stationary phase after glucose exhaustion): 1239 PubMed

Biological materials

  • Mutant:
  • Expression vector:
  • lacZ fusion:
  • GFP fusion:
  • two-hybrid system:
  • Antibody:

Labs working on this gene/protein

Your additional remarks

References