Difference between revisions of "RoxS"
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* '''Additional information:''' | * '''Additional information:''' | ||
− | ** the roxS RNA is degraded by the joined activities of [[rny|RNase Y]] (initial endonucleolytic cleavage) and RNase J1 (processive degradation) {{PubMed|25643072}} | + | ** the roxS RNA is degraded by the joined activities of [[rny|RNase Y]] (initial endonucleolytic cleavage) and [[rnjA|RNase J1]] (processive degradation) {{PubMed|25643072}} |
− | ** the roxS-ppnKB and roxS-sucC RNA duplexes form a cleavage site for RNase III {{PubMed|25643072}} | + | ** the ''[[roxS]]''-''[[ppnKB]]'' and ''[[roxS]]-[[sucC]]'' RNA duplexes form a cleavage site for [[rnc|RNase III]] {{PubMed|25643072}} |
=Biological materials = | =Biological materials = | ||
* '''Mutant:''' | * '''Mutant:''' | ||
− | + | ** available in [[Ciaran Condon]]'s lab {{PubMed|25643072}} | |
* '''Expression vector:''' | * '''Expression vector:''' | ||
Latest revision as of 12:37, 4 February 2015
Gene name | roxS |
Synonyms | rsaE |
Essential | no |
Product | trans-acting regulatory RNA |
Function | control of ppnKB and sucC-sucD expression |
Gene length | |
Immediate neighbours | yizD, yjbH |
Gene sequence (+200bp) | |
Genetic context |
Contents
Categories containing this gene/protein
This gene is a member of the following regulons
The RoxS regulon
The gene
Basic information
- Locus tag:
Phenotypes of a mutant
Database entries
- BsubCyc: no entry
- DBTBS entry: no entry
- SubtiList entry: no entry
- Structure:
Additional information
- Similar RNA:
The RNA
Basic information/ Evolution
- Catalyzed reaction/ biological activity: hybridizes to ppnKB and sucD mRNAs to inhibit their translation and to destabilize them PubMed
Extended information on the RNA
- Kinetic information
Database entries
- BsubCyc: ?
- Structure:
Additional information
Expression and regulation
- Operon: roxS PubMed
- Additional information:
Biological materials
- Mutant:
- available in Ciaran Condon's lab PubMed
- Expression vector:
- lacZ fusion:
Labs working on this gene/RNA
Ciaran Condon, Paris
Your additional remarks
References
Sylvain Durand, Frédérique Braun, Efthimia Lioliou, Cédric Romilly, Anne-Catherine Helfer, Laurianne Kuhn, Noé Quittot, Pierre Nicolas, Pascale Romby, Ciarán Condon
A nitric oxide regulated small RNA controls expression of genes involved in redox homeostasis in Bacillus subtilis.
PLoS Genet: 2015, 11(2);e1004957
[PubMed:25643072]
[WorldCat.org]
[DOI]
(I e)