Difference between revisions of "GsaB"
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* '''Additional information:''' | * '''Additional information:''' | ||
+ | ** number of protein molecules per cell (minimal medium with glucose and ammonium): 531 {{PubMed|24696501}} | ||
+ | ** number of protein molecules per cell (complex medium with amino acids, without glucose): 1080 {{PubMed|24696501}} | ||
=Biological materials = | =Biological materials = |
Revision as of 09:35, 17 April 2014
- Description: glutamate-1-semialdehyde aminotransferase
Gene name | gsaB |
Synonyms | |
Essential | no |
Product | glutamate-1-semialdehyde aminotransferase |
Function | biosynthesis of heme |
Gene expression levels in SubtiExpress: gsaB | |
Metabolic function and regulation of this protein in SubtiPathways: GsaB | |
MW, pI | 46 kDa, 5.644 |
Gene length, protein length | 1287 bp, 429 aa |
Immediate neighbours | ygaE, ygaF |
Sequences | Protein DNA DNA_with_flanks |
Genetic context This image was kindly provided by SubtiList
| |
Expression at a glance PubMed |
Contents
Categories containing this gene/protein
This gene is a member of the following regulons
The gene
Basic information
- Locus tag: BSU08710
Phenotypes of a mutant
Database entries
- BsubCyc: BSU08710
- DBTBS entry: no entry
- SubtiList entry: [1]
Additional information
The protein
Basic information/ Evolution
- Catalyzed reaction/ biological activity: (S)-4-amino-5-oxopentanoate = 5-aminolevulinate (according to Swiss-Prot)
- Protein family: HemL subfamily (according to Swiss-Prot)
- Paralogous protein(s): HemL
Extended information on the protein
- Kinetic information:
- Domains:
- Modification:
- Cofactor(s):
- Effectors of protein activity:
- Localization: cytoplasm (according to Swiss-Prot)
Database entries
- BsubCyc: BSU08710
- UniProt: P71084
- KEGG entry: [2]
- E.C. number: 5.4.3.8
Additional information
Expression and regulation
- Operon:
- Sigma factor:
- Regulation:
- Regulatory mechanism:
- Additional information:
Biological materials
- Mutant:
- Expression vector:
- lacZ fusion:
- GFP fusion:
- two-hybrid system:
- Antibody:
Labs working on this gene/protein
Your additional remarks
References
Honghua Ge, Xinhuai Lv, Jun Fan, Yongxiang Gao, Maikun Teng, Liwen Niu
Crystal structure of glutamate-1-semialdehyde aminotransferase from Bacillus subtilis with bound pyridoxamine-5'-phosphate.
Biochem Biophys Res Commun: 2010, 402(2);356-60
[PubMed:20946885]
[WorldCat.org]
[DOI]
(I p)