Difference between revisions of "PurR"
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* '''Additional information:''' | * '''Additional information:''' | ||
+ | ** number of protein molecules per cell (minimal medium with glucose and ammonium): 301 {{PubMed|24696501}} | ||
+ | ** number of protein molecules per cell (complex medium with amino acids, without glucose): 250 {{PubMed|24696501}} | ||
=Biological materials = | =Biological materials = |
Revision as of 09:26, 17 April 2014
- Description: transcription repressor of the pur operon
Gene name | purR |
Synonyms | yabI |
Essential | no |
Product | transcription repressor of the pur operon |
Function | regulation of purine biosynthesis |
Gene expression levels in SubtiExpress: purR | |
Interactions involving this protein in SubtInteract: PurR | |
Metabolic function and regulation of this protein in SubtiPathways: purR | |
MW, pI | 31 kDa, 5.771 |
Gene length, protein length | 855 bp, 285 aa |
Immediate neighbours | ispE, yabJ |
Sequences | Protein DNA DNA_with_flanks |
Genetic context This image was kindly provided by SubtiList
| |
Expression at a glance PubMed |
Contents
Categories containing this gene/protein
biosynthesis/ acquisition of nucleotides, transcription factors and their control
This gene is a member of the following regulons
The PurR regulon
The gene
Basic information
- Locus tag: BSU00470
Phenotypes of a mutant
Database entries
- BsubCyc: BSU00470
- DBTBS entry: [1]
- SubtiList entry: [2]
Additional information
The protein
Basic information/ Evolution
- Biological activity: transcriptional repressor of purine biosynthetic operons
- Protein family: purine/pyrimidine phosphoribosyltransferase family (according to Swiss-Prot)
- Paralogous protein(s):
Extended information on the protein
- Kinetic information:
- Domains:
- Modification:
- Cofactor(s):
- Effectors of protein activity: PRPP acts as inducer, binding results in release of PurR from the operator PubMed
Database entries
- BsubCyc: BSU00470
- UniProt: P37551
- KEGG entry: [3]
- E.C. number:
Additional information
requires YabJ for in vivo activity
Expression and regulation
- Sigma factor:
- Regulation: negative autoregulation, induction in the presence of PRPP PubMed
- Additional information:
Biological materials
- Mutant:
- Expression vector:
- lacZ fusion:
- GFP fusion:
- two-hybrid system:
- Antibody:
Labs working on this gene/protein
Your additional remarks
References