Difference between revisions of "FlgN"

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* '''Description:''' similar to flagellar protein <br/><br/>
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* '''Description:''' flagellar filament assembly protein <br/><br/>
  
 
{| align="right" border="1" cellpadding="2"  
 
{| align="right" border="1" cellpadding="2"  
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|style="background:#ABCDEF;" align="center"| '''Essential''' || no  
 
|style="background:#ABCDEF;" align="center"| '''Essential''' || no  
 
|-
 
|-
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|style="background:#ABCDEF;" align="center"| '''Product''' || unknown
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|style="background:#ABCDEF;" align="center"| '''Product''' || flagellar filament assembly protein
 
|-
 
|-
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|style="background:#ABCDEF;" align="center"|'''Function''' || unknown
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|style="background:#ABCDEF;" align="center"|'''Function''' || flagellar filament assembly
 
|-
 
|-
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|colspan="2" style="background:#FAF8CC;" align="center"| '''Gene expression levels in [http://subtiwiki.uni-goettingen.de/apps/expression/ ''Subti''Express]''': [http://subtiwiki.uni-goettingen.de/apps/expression/expression.php?search=BSU35420 yvyG]
+
|colspan="2" style="background:#FAF8CC;" align="center"| '''Gene expression levels in [http://subtiwiki.uni-goettingen.de/apps/expression/ ''Subti''Express]''': [http://subtiwiki.uni-goettingen.de/apps/expression/expression.php?search=BSU35420 flgN]
 
|-
 
|-
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|colspan="2" style="background:#FAF8CC;" align="center"| '''Interactions involving this protein in [http://subtiwiki.uni-goettingen.de/interact/ ''Subt''Interact]''': [http://subtiwiki.uni-goettingen.de/interact/index.php?protein=YvyG YvyG]
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|colspan="2" style="background:#FAF8CC;" align="center"| '''Interactions involving this protein in [http://subtiwiki.uni-goettingen.de/interact/ ''Subt''Interact]''': [http://subtiwiki.uni-goettingen.de/interact/index.php?protein=FlgN FlgN]
 
|-
 
|-
 
|style="background:#ABCDEF;" align="center"| '''MW, pI''' || 18 kDa, 8.81   
 
|style="background:#ABCDEF;" align="center"| '''MW, pI''' || 18 kDa, 8.81   
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<br/><br/><br/><br/>
 
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<br/><br/><br/><br/>
 
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<br/><br/><br/><br/>
 
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===Phenotypes of a mutant ===
 
===Phenotypes of a mutant ===
 +
* non-motile cells {{PubMed|24706744}}
  
 
=== Database entries ===
 
=== Database entries ===
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=== Additional information===
 
=== Additional information===
−
 
−
 
−
 
  
 
=The protein=
 
=The protein=
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* '''Kinetic information:'''
 
* '''Kinetic information:'''
  
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* '''Domains:'''  
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* '''[[Domains]]:'''  
  
 
* '''Modification:'''  
 
* '''Modification:'''  
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** phosphorylation on Tyr-49 [http://www.ncbi.nlm.nih.gov/sites/entrez/17218307 PubMed]
 
** phosphorylation on Tyr-49 [http://www.ncbi.nlm.nih.gov/sites/entrez/17218307 PubMed]
  
−
* '''Cofactor(s):'''
+
* '''[[Cofactors]]:'''
  
 
* '''Effectors of protein activity:'''
 
* '''Effectors of protein activity:'''
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=Expression and regulation=
 
=Expression and regulation=
 
* '''Operon:'''  
 
* '''Operon:'''  
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** ''[[comFA]]-[[comFB]]-[[comFC]]-[[yvyF]]-[[flgM]]-[[yvyG]]-[[flgK]]-[[flgL]]'' {{PubMed|8412657}}
+
** ''[[comFA]]-[[comFB]]-[[comFC]]-[[yvyF]]-[[flgM]]-[[flgN]]-[[flgK]]-[[flgL]]'' {{PubMed|8412657}}
−
** ''[[yvyF]]-[[flgM]]-[[yvyG]]-[[flgK]]-[[flgL]]'' {{PubMed|8045879}}
+
** ''[[yvyF]]-[[flgM]]-[[flgN]]-[[flgK]]-[[flgL]]'' {{PubMed|8045879}}
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** ''[[flgM]]-[[yvyG]]-[[flgK]]-[[flgL]]'' {{PubMed|21736639}}
+
** ''[[flgM]]-[[flgN]]-[[flgK]]-[[flgL]]'' {{PubMed|21736639}}
  
−
* '''Expression browser:''' [http://genome.jouy.inra.fr/cgi-bin/seb/viewdetail.py?id=yvyG_3639787_3640269_-1 yvyG] {{PubMed|22383849}}
+
* '''Expression browser:''' [http://genome.jouy.inra.fr/cgi-bin/seb/viewdetail.py?id=yvyG_3639787_3640269_-1 flgN] {{PubMed|22383849}}
  
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* '''Sigma factor:'''  
+
* '''[[Sigma factor]]:'''  
 
** ''[[comFA]]'': [[SigA]] {{PubMed|8412657}}
 
** ''[[comFA]]'': [[SigA]] {{PubMed|8412657}}
 
** ''[[yvyF]]'': [[SigD]] {{PubMed|8045879}}
 
** ''[[yvyF]]'': [[SigD]] {{PubMed|8045879}}
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=References=
 
=References=
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'''Additional publications:''' {{PubMed|21736639}}
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<pubmed>8412657 8045879 17218307, 15817382 22517742 24706744 21736639</pubmed>
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<pubmed>8412657 8045879 17218307, 15817382 22517742</pubmed>
 
  
 
[[Category:Protein-coding genes]]
 
[[Category:Protein-coding genes]]

Revision as of 14:33, 8 April 2014

  • Description: flagellar filament assembly protein

Gene name yvyG
Synonyms yviC
Essential no
Product flagellar filament assembly protein
Function flagellar filament assembly
Gene expression levels in SubtiExpress: flgN
Interactions involving this protein in SubtInteract: FlgN
MW, pI 18 kDa, 8.81
Gene length, protein length 480 bp, 160 aa
Immediate neighbours flgK, flgM
Sequences Protein DNA DNA_with_flanks
Genetic context
YvyG context.gif
This image was kindly provided by SubtiList
Expression at a glance   PubMed
YvyG expression.png















Categories containing this gene/protein

motility and chemotaxis, phosphoproteins

This gene is a member of the following regulons

ComK regulon, DegU regulon, SigD regulon

The gene

Basic information

  • Locus tag: BSU35420

Phenotypes of a mutant

Database entries

  • DBTBS entry: [1]
  • SubtiList entry: [2]

Additional information

The protein

Basic information/ Evolution

  • Catalyzed reaction/ biological activity:
  • Protein family:
  • Paralogous protein(s):

Extended information on the protein

  • Kinetic information:
  • Modification:
    • phosphorylated on Arg-60 PubMed
    • phosphorylation on Tyr-49 PubMed
  • Effectors of protein activity:

Database entries

  • Structure:
  • KEGG entry: [3]
  • E.C. number:

Additional information

Expression and regulation

  • Regulation:
  • Additional information:

Biological materials

  • Mutant:
  • Expression vector:
  • lacZ fusion:
  • GFP fusion:
  • two-hybrid system:
  • Antibody:

Labs working on this gene/protein

Your additional remarks

References

Lynne S Cairns, Victoria L Marlow, Taryn B Kiley, Christopher Birchall, Adam Ostrowski, Phillip D Aldridge, Nicola R Stanley-Wall
FlgN is required for flagellum-based motility by Bacillus subtilis.
J Bacteriol: 2014, 196(12);2216-26
[PubMed:24706744] [WorldCat.org] [DOI] (I p)

Alexander K W Elsholz, Kürsad Turgay, Stephan Michalik, Bernd Hessling, Katrin Gronau, Dan Oertel, Ulrike Mäder, Jörg Bernhardt, Dörte Becher, Michael Hecker, Ulf Gerth
Global impact of protein arginine phosphorylation on the physiology of Bacillus subtilis.
Proc Natl Acad Sci U S A: 2012, 109(19);7451-6
[PubMed:22517742] [WorldCat.org] [DOI] (I p)

Yi-Huang Hsueh, Loralyn M Cozy, Lok-To Sham, Rebecca A Calvo, Alina D Gutu, Malcolm E Winkler, Daniel B Kearns
DegU-phosphate activates expression of the anti-sigma factor FlgM in Bacillus subtilis.
Mol Microbiol: 2011, 81(4);1092-108
[PubMed:21736639] [WorldCat.org] [DOI] (I p)

Boris Macek, Ivan Mijakovic, Jesper V Olsen, Florian Gnad, Chanchal Kumar, Peter R Jensen, Matthias Mann
The serine/threonine/tyrosine phosphoproteome of the model bacterium Bacillus subtilis.
Mol Cell Proteomics: 2007, 6(4);697-707
[PubMed:17218307] [WorldCat.org] [DOI] (P p)

Mark J Pallen, Charles W Penn, Roy R Chaudhuri
Bacterial flagellar diversity in the post-genomic era.
Trends Microbiol: 2005, 13(4);143-9
[PubMed:15817382] [WorldCat.org] [DOI] (P p)

D B Mirel, P Lauer, M J Chamberlin
Identification of flagellar synthesis regulatory and structural genes in a sigma D-dependent operon of Bacillus subtilis.
J Bacteriol: 1994, 176(15);4492-500
[PubMed:8045879] [WorldCat.org] [DOI] (P p)

J A Londoño-Vallejo, D Dubnau
comF, a Bacillus subtilis late competence locus, encodes a protein similar to ATP-dependent RNA/DNA helicases.
Mol Microbiol: 1993, 9(1);119-31
[PubMed:8412657] [WorldCat.org] [DOI] (P p)

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