Difference between revisions of "MoaE"

From SubtiWiki
Jump to: navigation, search
Line 17: Line 17:
 
|-
 
|-
 
|colspan="2" style="background:#FAF8CC;" align="center"| '''Interactions involving this protein in [http://subtiwiki.uni-goettingen.de/interact/ ''Subt''Interact]''': [http://subtiwiki.uni-goettingen.de/interact/index.php?protein=MoaE MoaE]
 
|colspan="2" style="background:#FAF8CC;" align="center"| '''Interactions involving this protein in [http://subtiwiki.uni-goettingen.de/interact/ ''Subt''Interact]''': [http://subtiwiki.uni-goettingen.de/interact/index.php?protein=MoaE MoaE]
 +
|-
 +
|colspan="2" style="background:#FAF8CC;" align="center"| '''Metabolic function and regulation of this protein in [[SubtiPathways|''Subti''Pathways]]: <br/>[http://subtiwiki.uni-goettingen.de/subtipathways/search.php?enzyme=MoaE MoaE]'''
 
|-
 
|-
 
|style="background:#ABCDEF;" align="center"| '''MW, pI''' || 17 kDa, 4.746   
 
|style="background:#ABCDEF;" align="center"| '''MW, pI''' || 17 kDa, 4.746   

Revision as of 11:49, 8 April 2014

  • Description: molybdopterin synthase (large subunit), catalyses the transfer of sulfide from MoaD thiocarboxylate

Gene name moaE
Synonyms
Essential no
Product molybdopterin synthase (large subunit)
Function nitrate respiration
Gene expression levels in SubtiExpress: moaE
Interactions involving this protein in SubtInteract: MoaE
Metabolic function and regulation of this protein in SubtiPathways:
MoaE
MW, pI 17 kDa, 4.746
Gene length, protein length 471 bp, 157 aa
Immediate neighbours mobB, moaD
Sequences Protein DNA DNA_with_flanks
Genetic context
MoaE context.gif
This image was kindly provided by SubtiList
Expression at a glance   PubMed
MoaE expression.png















Categories containing this gene/protein

biosynthesis of cofactors

This gene is a member of the following regulons

The gene

Basic information

  • Locus tag: BSU14300

Phenotypes of a mutant

Database entries

  • DBTBS entry: no entry
  • SubtiList entry: [1]

Additional information

The protein

Basic information/ Evolution

  • Catalyzed reaction/ biological activity: catalyses the transfer of sulfide from MoaD thiocarboxylate
  • Protein family: moaE family (according to Swiss-Prot)
  • Paralogous protein(s):

Extended information on the protein

  • Kinetic information:
  • Modification:
  • Effectors of protein activity:

Database entries

  • KEGG entry: [2]
  • E.C. number:

Additional information

Expression and regulation

  • Regulation:
  • Regulatory mechanism:
  • Additional information:

Biological materials

  • Mutant:
  • Expression vector:
  • lacZ fusion:
  • GFP fusion:
  • two-hybrid system:
  • Antibody:

Labs working on this gene/protein

Your additional remarks

References

Reviews

Ralf R Mendel
The molybdenum cofactor.
J Biol Chem: 2013, 288(19);13165-72
[PubMed:23539623] [WorldCat.org] [DOI] (I p)

Tadhg P Begley, Steven E Ealick, Fred W McLafferty
Thiamin biosynthesis: still yielding fascinating biological chemistry.
Biochem Soc Trans: 2012, 40(3);555-60
[PubMed:22616866] [WorldCat.org] [DOI] (I p)

Original publications