Difference between revisions of "CypX"
| Line 54: | Line 54: | ||
=== Database entries === | === Database entries === | ||
| + | * '''BsubCyc:''' [http://bsubcyc.org/BSUB/NEW-IMAGE?type=NIL&object=BSU35060&redirect=T BSU35060] | ||
* '''DBTBS entry:''' no entry | * '''DBTBS entry:''' no entry | ||
| Line 92: | Line 93: | ||
=== Database entries === | === Database entries === | ||
| + | * '''BsubCyc:''' [http://bsubcyc.org/BSUB/NEW-IMAGE?type=NIL&object=BSU35060&redirect=T BSU35060] | ||
* '''Structure:''' [http://www.rcsb.org/pdb/cgi/explore.cgi?pdbId=3NC3 3NC3] {{PubMed|20690619}} | * '''Structure:''' [http://www.rcsb.org/pdb/cgi/explore.cgi?pdbId=3NC3 3NC3] {{PubMed|20690619}} | ||
Revision as of 14:54, 2 April 2014
- Description: cytochrome P450, cyclo-l-leucyl-l-leucyl dipeptide oxidase
| Gene name | cypX |
| Synonyms | |
| Essential | no |
| Product | cytochrome P450, cyclo-l-leucyl-l-leucyl dipeptide oxidase |
| Function | biosynthesis of the extracellular iron chelate pulcherrimin |
| Gene expression levels in SubtiExpress: cypX | |
| MW, pI | 45 kDa, 5.306 |
| Gene length, protein length | 1215 bp, 405 aa |
| Immediate neighbours | yvnA, yvmC |
| Sequences | Protein DNA DNA_with_flanks |
Genetic context 
This image was kindly provided by SubtiList
| |
Expression at a glance PubMed
| |
Contents
Categories containing this gene/protein
acquisition of iron, electron transport/ other, iron metabolism
This gene is a member of the following regulons
The gene
Basic information
- Locus tag: BSU35060
Phenotypes of a mutant
Database entries
- BsubCyc: BSU35060
- DBTBS entry: no entry
- SubtiList entry: [1]
Additional information
The protein
Basic information/ Evolution
- Catalyzed reaction/ biological activity:
- implicated in the three-step oxidative transformation of the diketopiperazine cyclo-l-leucyl-l-leucyl into pulcherriminic acid PubMed
- Protein family: cytochrome P450 family (according to Swiss-Prot)
- Paralogous protein(s):
Extended information on the protein
- Kinetic information:
- Domains:
- Modification:
- Cofactor(s):
- Effectors of protein activity:
Database entries
- BsubCyc: BSU35060
- UniProt: O34926
- KEGG entry: [2]
- E.C. number:
Additional information
Expression and regulation
- Regulation:
- Additional information:
Biological materials
- Mutant:
- Expression vector:
- lacZ fusion:
- GFP fusion:
- two-hybrid system:
- Antibody:
Labs working on this gene/protein
Your additional remarks
References
Onuma Chumsakul, Hiroki Takahashi, Taku Oshima, Takahiro Hishimoto, Shigehiko Kanaya, Naotake Ogasawara, Shu Ishikawa
Genome-wide binding profiles of the Bacillus subtilis transition state regulator AbrB and its homolog Abh reveals their interactive role in transcriptional regulation.
Nucleic Acids Res: 2011, 39(2);414-28
[PubMed:20817675]
[WorldCat.org]
[DOI]
(I p)
Max J Cryle, Stephen G Bell, Ilme Schlichting
Structural and biochemical characterization of the cytochrome P450 CypX (CYP134A1) from Bacillus subtilis: a cyclo-L-leucyl-L-leucyl dipeptide oxidase.
Biochemistry: 2010, 49(34);7282-96
[PubMed:20690619]
[WorldCat.org]
[DOI]
(I p)
R L Uffen, E Canale-Parola
Synthesis of pulcherriminic acid by Bacillus subtilis.
J Bacteriol: 1972, 111(1);86-93
[PubMed:4204912]
[WorldCat.org]
[DOI]
(P p)
