Difference between revisions of "RibC"
| Line 55: | Line 55: | ||
* essential {{PubMed|23109554}} | * essential {{PubMed|23109554}} | ||
=== Database entries === | === Database entries === | ||
| + | * '''BsubCyc:''' [http://bsubcyc.org/BSUB/NEW-IMAGE?type=NIL&object=BSU16670&redirect=T BSU16670] | ||
* '''DBTBS entry:''' no entry | * '''DBTBS entry:''' no entry | ||
| Line 92: | Line 93: | ||
=== Database entries === | === Database entries === | ||
| + | * '''BsubCyc:''' [http://bsubcyc.org/BSUB/NEW-IMAGE?type=NIL&object=BSU16670&redirect=T BSU16670] | ||
* '''Structure:''' [http://www.rcsb.org/pdb/explore/explore.do?pdbId=1S4M 1S4M] (from ''Thermotoga maritima'', 33% identity, 54% similarity) {{PubMed|15468322}} | * '''Structure:''' [http://www.rcsb.org/pdb/explore/explore.do?pdbId=1S4M 1S4M] (from ''Thermotoga maritima'', 33% identity, 54% similarity) {{PubMed|15468322}} | ||
Revision as of 13:45, 2 April 2014
- Description: riboflavin kinase / FAD synthase
| Gene name | ribC |
| Synonyms | |
| Essential | yes PubMed |
| Product | riboflavin kinase / FAD synthase |
| Function | FAD biosynthesis |
| Gene expression levels in SubtiExpress: ribC | |
| Metabolic function and regulation of this protein in SubtiPathways: ribC | |
| MW, pI | 35 kDa, 8.3 |
| Gene length, protein length | 948 bp, 316 aa |
| Immediate neighbours | truB, rpsO |
| Sequences | Protein DNA DNA_with_flanks |
Genetic context 
This image was kindly provided by SubtiList
| |
Expression at a glance PubMed
| |
Contents
Categories containing this gene/protein
biosynthesis of cofactors, essential genes
This gene is a member of the following regulons
The gene
Basic information
- Locus tag: BSU16670
Phenotypes of a mutant
- essential PubMed
Database entries
- BsubCyc: BSU16670
- DBTBS entry: no entry
- SubtiList entry: [1]
Additional information
The protein
Basic information/ Evolution
- Catalyzed reaction/ biological activity: ATP + riboflavin = ADP + FMN (according to Swiss-Prot)
- Protein family: ribF family (according to Swiss-Prot)
- Paralogous protein(s):
Extended information on the protein
- Kinetic information:
- Domains:
- Modification:
- Cofactor(s):
- Effectors of protein activity:
Database entries
- BsubCyc: BSU16670
- UniProt: P54575
- KEGG entry: [2]
Additional information
Expression and regulation
- Operon:
- Sigma factor:
- Regulation:
- Regulatory mechanism:
- Additional information:
Biological materials
- Mutant:
- Expression vector:
- lacZ fusion:
- GFP fusion:
- two-hybrid system:
- Antibody:
Labs working on this gene/protein
Your additional remarks
References
Kosei Tanaka, Christopher S Henry, Jenifer F Zinner, Edmond Jolivet, Matthew P Cohoon, Fangfang Xia, Vladimir Bidnenko, S Dusko Ehrlich, Rick L Stevens, Philippe Noirot
Building the repertoire of dispensable chromosome regions in Bacillus subtilis entails major refinement of cognate large-scale metabolic model.
Nucleic Acids Res: 2013, 41(1);687-99
[PubMed:23109554]
[WorldCat.org]
[DOI]
(I p)
Weiru Wang, Rosalind Kim, Hisao Yokota, Sung-Hou Kim
Crystal structure of flavin binding to FAD synthetase of Thermotoga maritima.
Proteins: 2005, 58(1);246-8
[PubMed:15468322]
[WorldCat.org]
[DOI]
(I p)
M Mack, A P van Loon, H P Hohmann
Regulation of riboflavin biosynthesis in Bacillus subtilis is affected by the activity of the flavokinase/flavin adenine dinucleotide synthetase encoded by ribC.
J Bacteriol: 1998, 180(4);950-5
[PubMed:9473052]
[WorldCat.org]
[DOI]
(P p)
