TatCY

• Description: component of the TatAY-TatCY twin-arginine translocase
  
  

Gene name	tatCY
Synonyms	ydiJ
Essential	no
Product	component of the twin-arginine translocation pathway
Function	TAT protein secretion
Gene expression levels in SubtiExpress: tatCY
Interactions involving this protein in SubtInteract: TatCY
Metabolic function and regulation of this protein in SubtiPathways: Protein secretion
MW, pI	28 kDa, 9.685
Gene length, protein length	762 bp, 254 aa
Immediate neighbours	tatAY, ydiK
Sequences	Protein DNA DNA_with_flanks
Genetic context This image was kindly provided by SubtiList
Expression at a glance   PubMed

Categories containing this gene/protein

protein secretion, membrane proteins

The gene

Basic information

• Locus tag: BSU05990

Database entries

• DBTBS entry: no entry

• SubtiList entry: [1]

The protein

Basic information/ Evolution

• Catalyzed reaction/ biological activity: secretion of YwbN and YkuE

• Protein family: tatC family (according to Swiss-Prot)

• Paralogous protein(s):

Extended information on the protein

• Kinetic information:

• Domains:

• Modification:

• Cofactors:

• Effectors of protein activity:

• Interactions:
  • TatAY-TatCY PubMed
  • TatAD-TatCY PubMed
  • TatAC-TatCY PubMed
  • WprA-TatCY PubMed

• Localization: cell membrane (according to Swiss-Prot), Polar (Septum) PubMed

Database entries

• Structure:

• UniProt: O05523

• KEGG entry: [2]

• E.C. number:

Additional information

• TatAY-TatCY-dependent export of YkuE and YwbN requires a functional WprA PubMed

Expression and regulation

• Operon:
  • ydiG-rex-tatAY-tatCY PubMed
  • tatAY-tatCY PubMed

• Expression browser: tatCY PubMed

• Sigma factor:

• Regulation: constitutitvely expressed PubMed

• Regulatory mechanism:

• Additional information:

Biological materials

• Mutant:

• Expression vector:

• lacZ fusion:

• GFP fusion:

• two-hybrid system:

• Antibody:

References

Reviews

Vivianne J Goosens, Carmine G Monteferrante, Jan Maarten van Dijl
The Tat system of Gram-positive bacteria.
Biochim Biophys Acta: 2014, 1843(8);1698-706
[PubMed:24140208] [WorldCat.org] [DOI] (P p)

Tracy Palmer, Ben C Berks
The twin-arginine translocation (Tat) protein export pathway.
Nat Rev Microbiol: 2012, 10(7);483-96
[PubMed:22683878] [WorldCat.org] [DOI] (I e)