Difference between revisions of "CotD"
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* '''[[Localization]]:''' | * '''[[Localization]]:''' | ||
| − | ** inner spore coat {{PubMed|19933362}} | + | ** inner spore coat {{PubMed|19933362}}, localization depends on [[SafA]] {{PubMed|22171814}} |
=== Database entries === | === Database entries === | ||
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* '''Expression browser:''' [http://genome.jouy.inra.fr/cgi-bin/seb/viewdetail.py?id=cotD_2332784_2333011_-1 cotD] {{PubMed|22383849}} | * '''Expression browser:''' [http://genome.jouy.inra.fr/cgi-bin/seb/viewdetail.py?id=cotD_2332784_2333011_-1 cotD] {{PubMed|22383849}} | ||
| − | * '''Sigma factor:''' [[SigK]] {{PubMed|15699190}} | + | * '''[[Sigma factor]]:''' [[SigK]] {{PubMed|15699190}} |
* '''Regulation:''' | * '''Regulation:''' | ||
| − | ** expressed late during sporulation in the mother cell ([[SigK]], [[SpoIIID]]) {{PubMed|15699190,7966271}} | + | ** expressed late during sporulation in the mother cell ([[SigK]], [[SpoIIID]], [[GerE]]) {{PubMed|15383836,15699190,7966271}} |
* '''Regulatory mechanism:''' | * '''Regulatory mechanism:''' | ||
** [[SpoIIID]]: transcription repression {{PubMed|7966271}} | ** [[SpoIIID]]: transcription repression {{PubMed|7966271}} | ||
| + | ** [[GerE]]: transcription activation {{PubMed|15383836}} | ||
* '''Additional information:''' | * '''Additional information:''' | ||
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=References= | =References= | ||
| − | <pubmed> 19933362,1518043,2821284,2492118,1691789,14651647, 15699190,7966271</pubmed> | + | <pubmed> 19933362,1518043,2821284,2492118,1691789,14651647, 15699190,7966271 22171814 15383836</pubmed> |
[[Category:Protein-coding genes]] | [[Category:Protein-coding genes]] | ||
Revision as of 17:36, 13 August 2013
- Description: spore coat protein (inner)
| Gene name | cotD |
| Synonyms | |
| Essential | no |
| Product | spore coat protein (inner) |
| Function | resistance of the spore |
| Gene expression levels in SubtiExpress: cotD | |
| MW, pI | 8 kDa, 7.373 |
| Gene length, protein length | 225 bp, 75 aa |
| Immediate neighbours | ypsA, yprB |
| Sequences | Protein DNA DNA_with_flanks |
Genetic context 
This image was kindly provided by SubtiList
| |
Expression at a glance PubMed
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Contents
Categories containing this gene/protein
This gene is a member of the following regulons
GerE regulon, SigK regulon, SpoIIID regulon
The gene
Basic information
- Locus tag: BSU22200
Phenotypes of a mutant
Database entries
- DBTBS entry: [1]
- SubtiList entry: [2]
Additional information
The protein
Basic information/ Evolution
- Catalyzed reaction/ biological activity:
- Protein family: nhaC Na(+)/H(+) antiporter family (according to Swiss-Prot)
- Paralogous protein(s):
Extended information on the protein
- Kinetic information:
- Domains:
- Modification:
- Cofactor(s):
- Effectors of protein activity:
Database entries
- Structure:
- UniProt: P07791
- KEGG entry: [3]
- E.C. number:
Additional information
Expression and regulation
- Operon: cotD (according to DBTBS)
- Regulatory mechanism:
- Additional information:
Biological materials
- Expression vector:
- lacZ fusion:
- GFP fusion:
- two-hybrid system:
- Antibody:
Labs working on this gene/protein
Your additional remarks
References
Peter T McKenney, Patrick Eichenberger
Dynamics of spore coat morphogenesis in Bacillus subtilis.
Mol Microbiol: 2012, 83(2);245-60
[PubMed:22171814]
[WorldCat.org]
[DOI]
(I p)
Daisuke Imamura, Ritsuko Kuwana, Hiromu Takamatsu, Kazuhito Watabe
Localization of proteins to different layers and regions of Bacillus subtilis spore coats.
J Bacteriol: 2010, 192(2);518-24
[PubMed:19933362]
[WorldCat.org]
[DOI]
(I p)
Leif Steil, Mónica Serrano, Adriano O Henriques, Uwe Völker
Genome-wide analysis of temporally regulated and compartment-specific gene expression in sporulating cells of Bacillus subtilis.
Microbiology (Reading): 2005, 151(Pt 2);399-420
[PubMed:15699190]
[WorldCat.org]
[DOI]
(P p)
Patrick Eichenberger, Masaya Fujita, Shane T Jensen, Erin M Conlon, David Z Rudner, Stephanie T Wang, Caitlin Ferguson, Koki Haga, Tsutomu Sato, Jun S Liu, Richard Losick
The program of gene transcription for a single differentiating cell type during sporulation in Bacillus subtilis.
PLoS Biol: 2004, 2(10);e328
[PubMed:15383836]
[WorldCat.org]
[DOI]
(I p)
Virginie Molle, Masaya Fujita, Shane T Jensen, Patrick Eichenberger, José E González-Pastor, Jun S Liu, Richard Losick
The Spo0A regulon of Bacillus subtilis.
Mol Microbiol: 2003, 50(5);1683-701
[PubMed:14651647]
[WorldCat.org]
[DOI]
(P p)
R Halberg, L Kroos
Sporulation regulatory protein SpoIIID from Bacillus subtilis activates and represses transcription by both mother-cell-specific forms of RNA polymerase.
J Mol Biol: 1994, 243(3);425-36
[PubMed:7966271]
[WorldCat.org]
[DOI]
(P p)
L Zheng, R Halberg, S Roels, H Ichikawa, L Kroos, R Losick
Sporulation regulatory protein GerE from Bacillus subtilis binds to and can activate or repress transcription from promoters for mother-cell-specific genes.
J Mol Biol: 1992, 226(4);1037-50
[PubMed:1518043]
[WorldCat.org]
[DOI]
(P p)
L B Zheng, R Losick
Cascade regulation of spore coat gene expression in Bacillus subtilis.
J Mol Biol: 1990, 212(4);645-60
[PubMed:1691789]
[WorldCat.org]
[DOI]
(P p)
L Kroos, B Kunkel, R Losick
Switch protein alters specificity of RNA polymerase containing a compartment-specific sigma factor.
Science: 1989, 243(4890);526-9
[PubMed:2492118]
[WorldCat.org]
[DOI]
(P p)
W Donovan, L B Zheng, K Sandman, R Losick
Genes encoding spore coat polypeptides from Bacillus subtilis.
J Mol Biol: 1987, 196(1);1-10
[PubMed:2821284]
[WorldCat.org]
[DOI]
(P p)
