Difference between revisions of "ImmR"

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Revision as of 12:37, 16 May 2013


Gene name immR
Synonyms ydcN
Essential no
Product transcriptional regulator (phage-related) (Xre family)
Function control of transfer of the mobile
genetic element ICEBs1
Gene expression levels in SubtiExpress: immR
Interactions involving this protein in SubtInteract: ImmR
MW, pI 14 kDa, 4.989
Gene length, protein length 381 bp, 127 aa
Immediate neighbours immA, xis
Sequences Protein DNA DNA_with_flanks
Genetic context
YdcN context.gif
This image was kindly provided by SubtiList
Expression at a glance   PubMed
ImmR expression.png
























Categories containing this gene/protein

transcription factors and their control, mobile genetic elements

This gene is a member of the following regulons

The ImmR regulon:

The gene

Basic information

  • Locus tag: BSU04820

Phenotypes of a mutant

Database entries

  • DBTBS entry: no entry
  • SubtiList entry: [1]

Additional information

The protein

Basic information/ Evolution

  • Catalyzed reaction/ biological activity:
  • Protein family:
  • Paralogous protein(s):

Extended information on the protein

  • Kinetic information:
  • Domains:
  • Modification:
  • Cofactor(s):
  • Effectors of protein activity: binding of RapI to ImmR results in loss of DNA-binding activity of ImmR and subsequently in induction of ImmR-repressed genes PubMed

Database entries

  • Structure:
  • KEGG entry: [2]
  • E.C. number:

Additional information

Expression and regulation

  • Operon:
  • Sigma factor:
  • Regulation:
  • Regulatory mechanism:
  • Additional information: ImmR is degraded by the anti-repressor ImmA PubMed

Biological materials

  • Mutant:
  • Expression vector:
  • lacZ fusion:
  • GFP fusion:
  • two-hybrid system:
  • Antibody:

Labs working on this gene/protein

Your additional remarks

References

Baundauna Bose, Alan D Grossman
Regulation of horizontal gene transfer in Bacillus subtilis by activation of a conserved site-specific protease.
J Bacteriol: 2011, 193(1);22-9
[PubMed:21036995] [WorldCat.org] [DOI] (I p)

Baundauna Bose, Jennifer M Auchtung, Catherine A Lee, Alan D Grossman
A conserved anti-repressor controls horizontal gene transfer by proteolysis.
Mol Microbiol: 2008, 70(3);570-82
[PubMed:18761623] [WorldCat.org] [DOI] (I p)

Jennifer M Auchtung, Catherine A Lee, Katherine L Garrison, Alan D Grossman
Identification and characterization of the immunity repressor (ImmR) that controls the mobile genetic element ICEBs1 of Bacillus subtilis.
Mol Microbiol: 2007, 64(6);1515-28
[PubMed:17511812] [WorldCat.org] [DOI] (P p)