Difference between revisions of "UvrC"
| Line 24: | Line 24: | ||
|style="background:#ABCDEF;" align="center"|'''Immediate neighbours''' || ''[[lysC]]'', ''[[trxA]]'' | |style="background:#ABCDEF;" align="center"|'''Immediate neighbours''' || ''[[lysC]]'', ''[[trxA]]'' | ||
|- | |- | ||
| − | |style="background:#FAF8CC;" align="center"|'''Sequences'''||[http://bsubcyc.org/BSUB/sequence-aa?type=GENE&object=BSU28490 Protein] [http://bsubcyc.org/BSUB/sequence?type=GENE&object=BSU28490 DNA] [http://bsubcyc.org/BSUB/seq-selector?chromosome=CHROM-1&object=BSU28490 | + | |style="background:#FAF8CC;" align="center"|'''Sequences'''||[http://bsubcyc.org/BSUB/sequence-aa?type=GENE&object=BSU28490 Protein] [http://bsubcyc.org/BSUB/sequence?type=GENE&object=BSU28490 DNA] [http://bsubcyc.org/BSUB/seq-selector?chromosome=CHROM-1&object=BSU28490 DNA_with_flanks] |
|- | |- | ||
|- | |- | ||
Revision as of 10:56, 14 May 2013
- Description: excinuclease ABC (subunit C)
| Gene name | uvrC |
| Synonyms | uvrB |
| Essential | no |
| Product | excinuclease ABC (subunit C) |
| Function | DNA repair after UV damage |
| Gene expression levels in SubtiExpress: uvrC | |
| Interactions involving this protein in SubtInteract: UvrC | |
| MW, pI | 69 kDa, 9.503 |
| Gene length, protein length | 1794 bp, 598 aa |
| Immediate neighbours | lysC, trxA |
| Sequences | Protein DNA DNA_with_flanks |
Genetic context 
This image was kindly provided by SubtiList
| |
Expression at a glance PubMed
| |
Contents
Categories containing this gene/protein
This gene is a member of the following regulons
The gene
Basic information
- Locus tag: BSU28490
Phenotypes of a mutant
Database entries
- DBTBS entry: [1]
- SubtiList entry: [2]
Additional information
The protein
Basic information/ Evolution
- Catalyzed reaction/ biological activity:
- Protein family: uvrC family (according to Swiss-Prot)
- Paralogous protein(s):
Extended information on the protein
- Kinetic information:
- Domains:
- Modification:
- Cofactor(s):
- Effectors of protein activity:
Database entries
- Structure: 3C65 (5' endonuclease domain, Geobacillus stearothermophilus)
- UniProt: P14951
- KEGG entry: [3]
- E.C. number:
Additional information
Expression and regulation
- Operon: uvrC PubMed
- Sigma factor:
- Additional information:
Biological materials
- Mutant:
- Expression vector:
- lacZ fusion:
- GFP fusion:
- two-hybrid system:
- Antibody:
Labs working on this gene/protein
Your additional remarks
References
Reviews
James J Truglio, Deborah L Croteau, Bennett Van Houten, Caroline Kisker
Prokaryotic nucleotide excision repair: the UvrABC system.
Chem Rev: 2006, 106(2);233-52
[PubMed:16464004]
[WorldCat.org]
[DOI]
(P p)
Bennett Van Houten, Deborah L Croteau, Matthew J DellaVecchia, Hong Wang, Caroline Kisker
'Close-fitting sleeves': DNA damage recognition by the UvrABC nuclease system.
Mutat Res: 2005, 577(1-2);92-117
[PubMed:15927210]
[WorldCat.org]
[DOI]
(P p)
A Sancar
Mechanisms of DNA excision repair.
Science: 1994, 266(5193);1954-6
[PubMed:7801120]
[WorldCat.org]
[DOI]
(P p)
Original Publications
