Difference between revisions of "TatAD"

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|style="background:#ABCDEF;" align="center"|'''Immediate neighbours''' || ''[[phoD]]'', ''[[tatCD]]''
 
|style="background:#ABCDEF;" align="center"|'''Immediate neighbours''' || ''[[phoD]]'', ''[[tatCD]]''
 
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|style="background:#FAF8CC;" align="center"|'''Sequences'''||[http://bsubcyc.org/BSUB/sequence-aa?type=GENE&object=BSU02630 Protein] [http://bsubcyc.org/BSUB/sequence?type=GENE&object=BSU02630 DNA] [http://bsubcyc.org/BSUB/seq-selector?chromosome=CHROM-1&object=BSU02630 Advanced_DNA]
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|style="background:#FAF8CC;" align="center"|'''Sequences'''||[http://bsubcyc.org/BSUB/sequence-aa?type=GENE&object=BSU02630 Protein] [http://bsubcyc.org/BSUB/sequence?type=GENE&object=BSU02630 DNA] [http://bsubcyc.org/BSUB/seq-selector?chromosome=CHROM-1&object=BSU02630 DNA_with_flanks]
 
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Revision as of 09:24, 14 May 2013

  • Description: component of the TatAD-TatCD twin-arginine translocase

Gene name tatAD
Synonyms yczB
Essential no
Product component of the twin-arginine
translocation pathway
Function TAT protein secretion
Gene expression levels in SubtiExpress: tatAD
Interactions involving this protein in SubtInteract: TatAD
Metabolic function and regulation of this protein in SubtiPathways:
Protein secretion
MW, pI 7 kDa, 9.693
Gene length, protein length 210 bp, 70 aa
Immediate neighbours phoD, tatCD
Sequences Protein DNA DNA_with_flanks
Genetic context
TatAD context.gif
This image was kindly provided by SubtiList
Expression at a glance   PubMed
TatAD expression.png















Categories containing this gene/protein

phosphate metabolism, protein secretion, membrane proteins

This gene is a member of the following regulons

PhoP regulon

The gene

Basic information

  • Locus tag: BSU02630

Phenotypes of a mutant

Database entries

  • DBTBS entry: no entry
  • SubtiList entry: [1]

Additional information

The protein

Basic information/ Evolution

  • Catalyzed reaction/ biological activity: translocation of PhoD PubMed
  • Protein family: tatA/E family (according to Swiss-Prot)
  • Paralogous protein(s):

Extended information on the protein

  • Kinetic information:
  • Domains:
  • Modification:
  • Cofactor(s):
  • Effectors of protein activity:
  • Localization: membrane (according to Swiss-Prot), forms foci at the division sites and cell poles, localization requires interaction with TatCD or TatCY PubMed

Database entries

  • KEGG entry: [2]
  • E.C. number:

Additional information

Expression and regulation

  • Regulation:
    • expressed under conditions of phosphate limitation (PhoP) PubMed
  • Regulatory mechanism:
  • Additional information:

Biological materials

  • Mutant:
  • Expression vector:
  • lacZ fusion:
  • GFP fusion:
  • two-hybrid system:
  • Antibody:

Labs working on this gene/protein

Oscar Kuipers, University of Groningen, The Netherlands Homepage

Your additional remarks

References

Reviews

Tracy Palmer, Ben C Berks
The twin-arginine translocation (Tat) protein export pathway.
Nat Rev Microbiol: 2012, 10(7);483-96
[PubMed:22683878] [WorldCat.org] [DOI] (I e)

Original publications