Difference between revisions of "UvrB"
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|style="background:#ABCDEF;" align="center"|'''Function''' || DNA repair after UV damage | |style="background:#ABCDEF;" align="center"|'''Function''' || DNA repair after UV damage | ||
|- | |- | ||
| − | |colspan="2" style="background:#FAF8CC;" align="center"| '''Gene expression levels in [http:// | + | |colspan="2" style="background:#FAF8CC;" align="center"| '''Gene expression levels in [http://subtiwiki.uni-goettingen.de/apps/expression/ ''Subti''Express]''': [http://subtiwiki.uni-goettingen.de/apps/expression/expression.php?search=BSU35170 uvrB] |
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|colspan="2" style="background:#FAF8CC;" align="center"| '''Interactions involving this protein in [http://cellpublisher.gobics.de/subtinteract/startpage/start/ ''Subt''Interact]''': [http://cellpublisher.gobics.de/subtinteract/interactionList/2/UvrB UvrB] | |colspan="2" style="background:#FAF8CC;" align="center"| '''Interactions involving this protein in [http://cellpublisher.gobics.de/subtinteract/startpage/start/ ''Subt''Interact]''': [http://cellpublisher.gobics.de/subtinteract/interactionList/2/UvrB UvrB] | ||
| Line 24: | Line 24: | ||
|style="background:#ABCDEF;" align="center"|'''Immediate neighbours''' || ''[[uvrA]]'', ''[[csbA]]'' | |style="background:#ABCDEF;" align="center"|'''Immediate neighbours''' || ''[[uvrA]]'', ''[[csbA]]'' | ||
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| − | | | + | |style="background:#FAF8CC;" align="center"|'''Sequences'''||[http://bsubcyc.org/BSUB/sequence-aa?type=GENE&object=BSU35170 Protein] [http://bsubcyc.org/BSUB/sequence?type=GENE&object=BSU35170 DNA] [http://bsubcyc.org/BSUB/seq-selector?chromosome=CHROM-1&object=BSU35170 Advanced_DNA] |
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|colspan="2" | '''Genetic context''' <br/> [[Image:uvrB_context.gif]] | |colspan="2" | '''Genetic context''' <br/> [[Image:uvrB_context.gif]] | ||
Revision as of 13:58, 13 May 2013
- Description: excinuclease ABC (subunit B)
| Gene name | uvrB |
| Synonyms | dinA, uvrA |
| Essential | no |
| Product | excinuclease ABC (subunit B) |
| Function | DNA repair after UV damage |
| Gene expression levels in SubtiExpress: uvrB | |
| Interactions involving this protein in SubtInteract: UvrB | |
| MW, pI | 76 kDa, 5.26 |
| Gene length, protein length | 1983 bp, 661 aa |
| Immediate neighbours | uvrA, csbA |
| Sequences | Protein DNA Advanced_DNA |
Genetic context 
This image was kindly provided by SubtiList
| |
Expression at a glance PubMed
| |
Contents
Categories containing this gene/protein
This gene is a member of the following regulons
The gene
Basic information
- Locus tag: BSU35170
Phenotypes of a mutant
Database entries
- DBTBS entry: [1]
- SubtiList entry: [2]
Additional information
- A mutation was found in this gene after evolution under relaxed selection for sporulation PubMed
The protein
Basic information/ Evolution
- Catalyzed reaction/ biological activity:
- Protein family: uvrB family (according to Swiss-Prot)
- Paralogous protein(s):
Extended information on the protein
- Kinetic information:
- Domains:
- Modification:
- Cofactor(s):
- Effectors of protein activity:
- Localization: cytoplasm (according to Swiss-Prot)
Database entries
- Structure: 2NMV (bound to fluorescein-adducted DNA); 2D7D ternary complex involving UvrB* (a C-terminal truncation of full-length UvrB), a polythymine trinucleotide and ADP PubMed
- UniProt: P37954
- KEGG entry: [3]
- E.C. number:
Additional information
Expression and regulation
- Sigma factor:
- Additional information:
Biological materials
- Mutant: GP1175 (del uvrAB::ermC) (available in the Stülke lab)
- Expression vector:
- lacZ fusion:
- GFP fusion:
- two-hybrid system:
- Antibody:
Labs working on this gene/protein
Your additional remarks
References
Reviews
Original Publications
