Difference between revisions of "FisB"
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|style="background:#ABCDEF;" align="center"|'''Function''' || release of the forespore into the mother cell cytoplasm | |style="background:#ABCDEF;" align="center"|'''Function''' || release of the forespore into the mother cell cytoplasm | ||
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| − | |colspan="2" style="background:#FAF8CC;" align="center"| '''Gene expression levels in [http:// | + | |colspan="2" style="background:#FAF8CC;" align="center"| '''Gene expression levels in [http://subtiwiki.uni-goettingen.de/apps/expression/ ''Subti''Express]''': [http://subtiwiki.uni-goettingen.de/apps/expression/expression.php?search=BSU32350 fisB] |
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|style="background:#ABCDEF;" align="center"| '''MW, pI''' || 27 kDa, 9.529 | |style="background:#ABCDEF;" align="center"| '''MW, pI''' || 27 kDa, 9.529 | ||
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|style="background:#ABCDEF;" align="center"|'''Immediate neighbours''' || ''[[lytH]]'', ''[[yunC]]'' | |style="background:#ABCDEF;" align="center"|'''Immediate neighbours''' || ''[[lytH]]'', ''[[yunC]]'' | ||
|- | |- | ||
| − | | | + | |style="background:#FAF8CC;" align="center"|'''Sequences'''||[http://bsubcyc.org/BSUB/sequence-aa?type=GENE&object=BSU32350 Protein] [http://bsubcyc.org/BSUB/sequence?type=GENE&object=BSU32350 DNA] [http://bsubcyc.org/BSUB/seq-selector?chromosome=CHROM-1&object=BSU32350 Advanced_DNA] |
|- | |- | ||
|colspan="2" | '''Genetic context''' <br/> [[Image:yunB_context.gif]] | |colspan="2" | '''Genetic context''' <br/> [[Image:yunB_context.gif]] | ||
Revision as of 13:46, 13 May 2013
- Description: membrane fission protein, mediates membrane fission during sporulation
| Gene name | fisB |
| Synonyms | yunB |
| Essential | no |
| Product | membrane fission protein |
| Function | release of the forespore into the mother cell cytoplasm |
| Gene expression levels in SubtiExpress: fisB | |
| MW, pI | 27 kDa, 9.529 |
| Gene length, protein length | 762 bp, 254 aa |
| Immediate neighbours | lytH, yunC |
| Sequences | Protein DNA Advanced_DNA |
Genetic context 
This image was kindly provided by SubtiList
| |
Expression at a glance PubMed
| |
Contents
Categories containing this gene/protein
membrane dynamics, sporulation proteins, membrane proteins
This gene is a member of the following regulons
The gene
Basic information
- Locus tag: BSU32350
Phenotypes of a mutant
- reduced sporulation efficiency (12 - 15%) PubMed
Database entries
- DBTBS entry: [1]
- SubtiList entry: [2]
Additional information
The protein
Basic information/ Evolution
- Catalyzed reaction/ biological activity:
- mediates membrane fission during sporulation PubMed
- binds cardiolipin PubMed
- Protein family:
- Paralogous protein(s):
Extended information on the protein
- Kinetic information:
- Domains:
- Modification:
- Cofactor(s):
- Effectors of protein activity:
Database entries
- Structure:
- UniProt: O32131
- KEGG entry: [3]
- E.C. number:
Additional information
Expression and regulation
- Operon: fisB PubMed
- Regulatory mechanism:
- Additional information:
Biological materials
- Mutant:
- Expression vector:
- lacZ fusion:
- GFP fusion:
- two-hybrid system:
- Antibody:
Labs working on this gene/protein
Your additional remarks
References
Reviews
Irene S Tan, Kumaran S Ramamurthi
Membrane remodeling: FisB will do in a pinch.
Curr Biol: 2013, 23(6);R251-3
[PubMed:23518060]
[WorldCat.org]
[DOI]
(I p)
Original publications
Thierry Doan, Jeff Coleman, Kathleen A Marquis, Alex J Meeske, Briana M Burton, Erdem Karatekin, David Z Rudner
FisB mediates membrane fission during sporulation in Bacillus subtilis.
Genes Dev: 2013, 27(3);322-34
[PubMed:23388828]
[WorldCat.org]
[DOI]
(I p)
Leif Steil, Mónica Serrano, Adriano O Henriques, Uwe Völker
Genome-wide analysis of temporally regulated and compartment-specific gene expression in sporulating cells of Bacillus subtilis.
Microbiology (Reading): 2005, 151(Pt 2);399-420
[PubMed:15699190]
[WorldCat.org]
[DOI]
(P p)
Patrick Eichenberger, Shane T Jensen, Erin M Conlon, Christiaan van Ooij, Jessica Silvaggi, José Eduardo González-Pastor, Masaya Fujita, Sigal Ben-Yehuda, Patrick Stragier, Jun S Liu, Richard Losick
The sigmaE regulon and the identification of additional sporulation genes in Bacillus subtilis.
J Mol Biol: 2003, 327(5);945-72
[PubMed:12662922]
[WorldCat.org]
[DOI]
(P p)
