Difference between revisions of "LytH"

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|style="background:#ABCDEF;" align="center"|'''Function''' || endospore cortex maturation
 
|style="background:#ABCDEF;" align="center"|'''Function''' || endospore cortex maturation
 
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|colspan="2" style="background:#FAF8CC;" align="center"| '''Gene expression levels in [http://cellpublisher.gobics.de/subtiexpress/ ''Subti''Express]''': [http://cellpublisher.gobics.de/subtiexpress/bsu/BSU32340 lytH]
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|colspan="2" style="background:#FAF8CC;" align="center"| '''Gene expression levels in [http://subtiwiki.uni-goettingen.de/apps/expression/ ''Subti''Express]''': [http://subtiwiki.uni-goettingen.de/apps/expression/expression.php?search=BSU32340 lytH]
 
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|style="background:#ABCDEF;" align="center"| '''MW, pI''' || 39 kDa, 6.893   
 
|style="background:#ABCDEF;" align="center"| '''MW, pI''' || 39 kDa, 6.893   
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|style="background:#ABCDEF;" align="center"|'''Immediate neighbours''' || ''[[lipA]]'', ''[[fisB]]''
 
|style="background:#ABCDEF;" align="center"|'''Immediate neighbours''' || ''[[lipA]]'', ''[[fisB]]''
 
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|colspan="2" style="background:#FAF8CC;" align="center"|'''Get the DNA and protein [http://srs.ebi.ac.uk/srsbin/cgi-bin/wgetz?-e+&#91;EMBLCDS:CAB15224&#93;+-newId sequences] <br/> (Barbe ''et al.'', 2009)'''
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|style="background:#FAF8CC;" align="center"|'''Sequences'''||[http://bsubcyc.org/BSUB/sequence-aa?type=GENE&object=BSU32340 Protein] [http://bsubcyc.org/BSUB/sequence?type=GENE&object=BSU32340 DNA] [http://bsubcyc.org/BSUB/seq-selector?chromosome=CHROM-1&object=BSU32340 Advanced_DNA]
 
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|colspan="2" | '''Genetic context''' <br/> [[Image:yunA_context.gif]]
 
|colspan="2" | '''Genetic context''' <br/> [[Image:yunA_context.gif]]

Revision as of 13:46, 13 May 2013

  • Description: differentiation-associated peptidoglycan hydrolase involved in endospore cortex maturation

Gene name lytH
Synonyms yunA, yutA
Essential no
Product peptidoglycan hydrolase
Function endospore cortex maturation
Gene expression levels in SubtiExpress: lytH
MW, pI 39 kDa, 6.893
Gene length, protein length 1047 bp, 349 aa
Immediate neighbours lipA, fisB
Sequences Protein DNA Advanced_DNA
Genetic context
YunA context.gif
This image was kindly provided by SubtiList
Expression at a glance   PubMed
LytH expression.png















Categories containing this gene/protein

cell wall/ other, sporulation proteins

This gene is a member of the following regulons

SigK regulon

The gene

Basic information

  • Locus tag: BSU32340

Phenotypes of a mutant

Database entries

  • DBTBS entry: no entry
  • SubtiList entry: [1]

Additional information

The protein

Basic information/ Evolution

  • Catalyzed reaction/ biological activity:
  • Protein family: peptidase M23B family (according to Swiss-Prot)
  • Paralogous protein(s):

Extended information on the protein

  • Kinetic information:
  • Domains:
  • Modification:
  • Cofactor(s):
  • Effectors of protein activity:

Database entries

  • Structure:
  • KEGG entry: [2]
  • E.C. number:

Additional information

Expression and regulation

  • Regulation:
    • expressed late during sporulation in the mother cell (SigK) PubMed
  • Regulatory mechanism:
  • Additional information:

Biological materials

  • Mutant:
  • Expression vector:
  • lacZ fusion:
  • GFP fusion:
  • two-hybrid system:
  • Antibody:

Labs working on this gene/protein

Your additional remarks

References

Gavin J Horsburgh, Abdelmadjid Atrih, Simon J Foster
Characterization of LytH, a differentiation-associated peptidoglycan hydrolase of Bacillus subtilis involved in endospore cortex maturation.
J Bacteriol: 2003, 185(13);3813-20
[PubMed:12813075] [WorldCat.org] [DOI] (P p)