Difference between revisions of "ComC"

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|style="background:#ABCDEF;" align="center"|'''Function''' || [[genetic competence]]
 
|style="background:#ABCDEF;" align="center"|'''Function''' || [[genetic competence]]
 
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|colspan="2" style="background:#FAF8CC;" align="center"| '''Gene expression levels in [http://cellpublisher.gobics.de/subtiexpress/ ''Subti''Express]''': [http://cellpublisher.gobics.de/subtiexpress/bsu/BSU28070 comC]
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|colspan="2" style="background:#FAF8CC;" align="center"| '''Gene expression levels in [http://subtiwiki.uni-goettingen.de/apps/expression/ ''Subti''Express]''': [http://subtiwiki.uni-goettingen.de/apps/expression/expression.php?search=BSU28070 comC]
 
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|colspan="2" style="background:#FAF8CC;" align="center"| '''Interactions involving this protein in [http://cellpublisher.gobics.de/subtinteract/startpage/start/ ''Subt''Interact]''': [http://cellpublisher.gobics.de/subtinteract/interactionList/2/ComC ComC]
 
|colspan="2" style="background:#FAF8CC;" align="center"| '''Interactions involving this protein in [http://cellpublisher.gobics.de/subtinteract/startpage/start/ ''Subt''Interact]''': [http://cellpublisher.gobics.de/subtinteract/interactionList/2/ComC ComC]
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|style="background:#ABCDEF;" align="center"|'''Immediate neighbours''' || ''[[spoIIB]]'', ''[[folC]]''
 
|style="background:#ABCDEF;" align="center"|'''Immediate neighbours''' || ''[[spoIIB]]'', ''[[folC]]''
 
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|colspan="2" style="background:#FAF8CC;" align="center"|'''Get the DNA and protein [http://srs.ebi.ac.uk/srsbin/cgi-bin/wgetz?-e+&#91;EMBLCDS:CAB14767&#93;+-newId sequences] <br/> (Barbe ''et al.'', 2009)'''
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|style="background:#FAF8CC;" align="center"|'''Sequences'''||[http://bsubcyc.org/BSUB/sequence-aa?type=GENE&object=BSU28070 Protein] [http://bsubcyc.org/BSUB/sequence?type=GENE&object=BSU28070 DNA] [http://bsubcyc.org/BSUB/seq-selector?chromosome=CHROM-1&object=BSU28070 Advanced_DNA]
 
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Revision as of 13:29, 13 May 2013

Gene name comC
Synonyms
Essential no
Product processing protease
Function genetic competence
Gene expression levels in SubtiExpress: comC
Interactions involving this protein in SubtInteract: ComC
Metabolic function and regulation of this protein in SubtiPathways:
Protein secretion
MW, pI 26 kDa, 9.843
Gene length, protein length 744 bp, 248 aa
Immediate neighbours spoIIB, folC
Sequences Protein DNA Advanced_DNA
Genetic context
ComC context.gif
This image was kindly provided by SubtiList
Expression at a glance   PubMed
ComC expression.png


























Categories containing this gene/protein

genetic competence, protein secretion, membrane proteins

This gene is a member of the following regulons

ComK regulon

The gene

Basic information

  • Locus tag: BSU28070

Phenotypes of a mutant

Database entries

  • DBTBS entry: [1]
  • SubtiList entry: [2]

Additional information

The protein

Basic information/ Evolution

  • Catalyzed reaction/ biological activity:
    • processing and translocation of ComGC, ComGD, ComGE and ComGG PubMed
    • Typically cleaves a -Gly-|-Phe- bond to release an N-terminal, basic peptide of 5-8 residues from type IV prepilin, and then N-methylates the new N-terminal amino group, the methyl donor being S-adenosyl-L-methionine (according to Swiss-Prot)
  • Protein family: peptidase A24 family (according to Swiss-Prot)
  • Paralogous protein(s):

Extended information on the protein

  • Kinetic information:
  • Domains:
  • Modification:
  • Cofactor(s):
  • Effectors of protein activity:

Database entries

  • Structure:
  • KEGG entry: [3]
  • E.C. number:

Additional information

Expression and regulation

  • Regulation:
  • Regulatory mechanism:
  • Additional information:

Biological materials

  • Mutant:
  • Expression vector:
  • lacZ fusion:
  • GFP fusion:
  • two-hybrid system:
  • Antibody:

Labs working on this gene/protein

Your additional remarks

References

Reviews

Original publications