Difference between revisions of "YlmB"
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|style="background:#ABCDEF;" align="center"|'''Function''' || thiamine salvage | |style="background:#ABCDEF;" align="center"|'''Function''' || thiamine salvage | ||
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| − | |colspan="2" style="background:#FAF8CC;" align="center"| '''Gene expression levels in [http:// | + | |colspan="2" style="background:#FAF8CC;" align="center"| '''Gene expression levels in [http://subtiwiki.uni-goettingen.de/apps/expression/ ''Subti''Express]''': [http://subtiwiki.uni-goettingen.de/apps/expression/expression.php?search=BSU15350 ylmB] |
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|colspan="2" style="background:#FAF8CC;" align="center"| '''Metabolic function and regulation of this protein in [[SubtiPathways|''Subti''Pathways]]: <br/>[http://subtiwiki.uni-goettingen.de/pathways/thiamin.html Thiamin]''' | |colspan="2" style="background:#FAF8CC;" align="center"| '''Metabolic function and regulation of this protein in [[SubtiPathways|''Subti''Pathways]]: <br/>[http://subtiwiki.uni-goettingen.de/pathways/thiamin.html Thiamin]''' | ||
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|style="background:#ABCDEF;" align="center"|'''Immediate neighbours''' || ''[[ylmA]]'', ''[[ylmC]]'' | |style="background:#ABCDEF;" align="center"|'''Immediate neighbours''' || ''[[ylmA]]'', ''[[ylmC]]'' | ||
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| − | | | + | |style="background:#FAF8CC;" align="center"|'''Sequences'''||[http://bsubcyc.org/BSUB/sequence-aa?type=GENE&object=BSU15350 Protein] [http://bsubcyc.org/BSUB/sequence?type=GENE&object=BSU15350 DNA] [http://bsubcyc.org/BSUB/seq-selector?chromosome=CHROM-1&object=BSU15350 Advanced_DNA] |
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Revision as of 12:46, 13 May 2013
- Description: N-formyl-4-amino-5-aminomethyl-2-methylpyrimidine deformylase
| Gene name | ylmB |
| Synonyms | |
| Essential | no |
| Product | N-formyl-4-amino-5-aminomethyl-2-methylpyrimidine deformylase |
| Function | thiamine salvage |
| Gene expression levels in SubtiExpress: ylmB | |
| Metabolic function and regulation of this protein in SubtiPathways: Thiamin | |
| MW, pI | 47 kDa, 4.981 |
| Gene length, protein length | 1278 bp, 426 aa |
| Immediate neighbours | ylmA, ylmC |
| Sequences | Protein DNA Advanced_DNA |
Genetic context 
This image was kindly provided by SubtiList
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Expression at a glance PubMed
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Contents
Categories containing this gene/protein
This gene is a member of the following regulons
The gene
Basic information
- Locus tag: BSU15350
Phenotypes of a mutant
Database entries
- DBTBS entry: no entry
- SubtiList entry: [1]
Additional information
The protein
Basic information/ Evolution
- Catalyzed reaction/ biological activity: N-formyl-4-amino-5-aminomethyl-2-methylpyrimidine + H2O = formate + 4-amino-5-aminomethyl-2-methylpyrimidine (according to Swiss-Prot)
- Protein family:
- Paralogous protein(s): YodQ
Extended information on the protein
- Kinetic information:
- Domains:
- Modification:
- Cofactor(s):Binds 2 zinc or cobalt ions per subunit (according to Swiss-Prot)
- Effectors of protein activity:
Database entries
- Structure:
- UniProt: O31724
- KEGG entry: [2]
- E.C. number:
Additional information
Expression and regulation
- Operon:
- Regulatory mechanism:
- Additional information:
Biological materials
- Mutant:
- Expression vector:
- lacZ fusion:
- GFP fusion:
- two-hybrid system:
- Antibody:
Labs working on this gene/protein
Your additional remarks
References
Amy Haas Jenkins, Ghislain Schyns, Sébastien Potot, Guangxing Sun, Tadhg P Begley
A new thiamin salvage pathway.
Nat Chem Biol: 2007, 3(8);492-7
[PubMed:17618314]
[WorldCat.org]
[DOI]
(P p)
Dmitry A Rodionov, Alexey G Vitreschak, Andrey A Mironov, Mikhail S Gelfand
Comparative genomics of thiamin biosynthesis in procaryotes. New genes and regulatory mechanisms.
J Biol Chem: 2002, 277(50);48949-59
[PubMed:12376536]
[WorldCat.org]
[DOI]
(P p)
