Difference between revisions of "ThiO"

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|style="background:#ABCDEF;" align="center"|'''Function''' || biosynthesis of thiamine
 
|style="background:#ABCDEF;" align="center"|'''Function''' || biosynthesis of thiamine
 
|-
 
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|colspan="2" style="background:#FAF8CC;" align="center"| '''Gene expression levels in [http://cellpublisher.gobics.de/subtiexpress/ ''Subti''Express]''': [http://cellpublisher.gobics.de/subtiexpress/bsu/BSU11670 thiO]
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|colspan="2" style="background:#FAF8CC;" align="center"| '''Gene expression levels in [http://subtiwiki.uni-goettingen.de/apps/expression/ ''Subti''Express]''': [http://subtiwiki.uni-goettingen.de/apps/expression/expression.php?search=BSU11670 thiO]
 
|-
 
|-
 
|colspan="2" style="background:#FAF8CC;" align="center"| '''Metabolic function and regulation of this protein in [[SubtiPathways|''Subti''Pathways]]: <br/>[http://subtiwiki.uni-goettingen.de/pathways/thiamin.html Thiamin]'''
 
|colspan="2" style="background:#FAF8CC;" align="center"| '''Metabolic function and regulation of this protein in [[SubtiPathways|''Subti''Pathways]]: <br/>[http://subtiwiki.uni-goettingen.de/pathways/thiamin.html Thiamin]'''
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|style="background:#ABCDEF;" align="center"|'''Immediate neighbours''' || ''[[tenI]]'', ''[[thiS]]''
 
|style="background:#ABCDEF;" align="center"|'''Immediate neighbours''' || ''[[tenI]]'', ''[[thiS]]''
 
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|colspan="2" style="background:#FAF8CC;" align="center"|'''Get the DNA and protein [http://srs.ebi.ac.uk/srsbin/cgi-bin/wgetz?-e+&#91;EMBLCDS:CAB13024&#93;+-newId sequences] <br/> (Barbe ''et al.'', 2009)'''
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|style="background:#FAF8CC;" align="center"|'''Sequences'''||[http://bsubcyc.org/BSUB/sequence-aa?type=GENE&object=BSU11670 Protein] [http://bsubcyc.org/BSUB/sequence?type=GENE&object=BSU11670 DNA] [http://bsubcyc.org/BSUB/seq-selector?chromosome=CHROM-1&object=BSU11670 Advanced_DNA]
 
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|colspan="2" | '''Genetic context''' <br/> [[Image:goxB_context.gif]]
 
|colspan="2" | '''Genetic context''' <br/> [[Image:goxB_context.gif]]

Revision as of 12:33, 13 May 2013

  • Description: FAD-dependent glycine oxidase

Gene name thiO
Synonyms goxB, yjbR
Essential no
Product glycine oxidase
Function biosynthesis of thiamine
Gene expression levels in SubtiExpress: thiO
Metabolic function and regulation of this protein in SubtiPathways:
Thiamin
MW, pI 40 kDa, 5.898
Gene length, protein length 1107 bp, 369 aa
Immediate neighbours tenI, thiS
Sequences Protein DNA Advanced_DNA
Genetic context
GoxB context.gif
This image was kindly provided by SubtiList
Expression at a glance   PubMed
ThiO expression.png




























Categories containing this gene/protein

biosynthesis of cofactors

This gene is a member of the following regulons

Thi-box

The gene

Basic information

  • Locus tag: BSU11670

Phenotypes of a mutant

Database entries

  • DBTBS entry: [1]
  • SubtiList entry: [2]

Additional information

The protein

Basic information/ Evolution

  • Catalyzed reaction/ biological activity: Glycine + H2O + O2 = glyoxylate + NH3 + H2O2 (according to Swiss-Prot)
  • Protein family: DAMOX/DASOX family (according to Swiss-Prot)
  • Paralogous protein(s):

Extended information on the protein

  • Kinetic information:
  • Domains:
  • Cofactor(s):
  • Effectors of protein activity:

Database entries

  • Structure: 1NG3 (complex with acetyl-glycine), 1RYI
  • KEGG entry: [3]

Additional information

Expression and regulation

  • Sigma factor:
  • Additional information:

Biological materials

  • Mutant:
  • Expression vector:
  • lacZ fusion:
  • GFP fusion:
  • two-hybrid system:
  • Antibody:

Labs working on this gene/protein

Your additional remarks

References

Reviews

Original publications