Difference between revisions of "Fra"

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|style="background:#ABCDEF;" align="center"|'''Function''' || intracellular iron channeling, biosynthesis of iron-sulfur clusters
 
|style="background:#ABCDEF;" align="center"|'''Function''' || intracellular iron channeling, biosynthesis of iron-sulfur clusters
 
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|colspan="2" style="background:#FAF8CC;" align="center"| '''Gene expression levels in [http://cellpublisher.gobics.de/subtiexpress/ ''Subti''Express]''': [http://cellpublisher.gobics.de/subtiexpress/bsu/BSU05750 fra]
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|colspan="2" style="background:#FAF8CC;" align="center"| '''Gene expression levels in [http://subtiwiki.uni-goettingen.de/apps/expression/ ''Subti''Express]''': [http://subtiwiki.uni-goettingen.de/apps/expression/expression.php?search=BSU05750 fra]
 
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|colspan="2" style="background:#FAF8CC;" align="center"| '''Interactions involving this protein in [http://cellpublisher.gobics.de/subtinteract/startpage/start/ ''Subt''Interact]''': [http://cellpublisher.gobics.de/subtinteract/interactionList/2/Fra Fra]
 
|colspan="2" style="background:#FAF8CC;" align="center"| '''Interactions involving this protein in [http://cellpublisher.gobics.de/subtinteract/startpage/start/ ''Subt''Interact]''': [http://cellpublisher.gobics.de/subtinteract/interactionList/2/Fra Fra]
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|style="background:#ABCDEF;" align="center"|'''Immediate neighbours''' || ''[[phoB]]'', ''[[ydhH]]''
 
|style="background:#ABCDEF;" align="center"|'''Immediate neighbours''' || ''[[phoB]]'', ''[[ydhH]]''
 
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|colspan="2" style="background:#FAF8CC;" align="center"|'''Get the DNA and protein [http://srs.ebi.ac.uk/srsbin/cgi-bin/wgetz?-e+&#91;EMBLCDS:CAB12394&#93;+-newId sequences] <br/> (Barbe ''et al.'', 2009)'''
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|style="background:#FAF8CC;" align="center"|'''Sequences'''||[http://bsubcyc.org/BSUB/sequence-aa?type=GENE&object=BSU05750 Protein] [http://bsubcyc.org/BSUB/sequence?type=GENE&object=BSU05750 DNA] [http://bsubcyc.org/BSUB/seq-selector?chromosome=CHROM-1&object=BSU05750 Advanced_DNA]
 
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|colspan="2" | '''Genetic context''' <br/> [[Image:ydhG_context.gif]]
 
|colspan="2" | '''Genetic context''' <br/> [[Image:ydhG_context.gif]]

Revision as of 12:15, 13 May 2013

  • Description: frataxin-like protein, required for the biosynthesis of iron-sulfur clusters

Gene name fra
Synonyms ydhG
Essential no
Product frataxin-like protein
Function intracellular iron channeling, biosynthesis of iron-sulfur clusters
Gene expression levels in SubtiExpress: fra
Interactions involving this protein in SubtInteract: Fra
MW, pI 14 kDa, 5.377
Gene length, protein length 369 bp, 123 aa
Immediate neighbours phoB, ydhH
Sequences Protein DNA Advanced_DNA
Genetic context
YdhG context.gif
This image was kindly provided by SubtiList
Expression at a glance   PubMed
Fra expression.png
























Categories containing this gene/protein

iron metabolism

This gene is a member of the following regulons

The gene

Basic information

  • Locus tag: BSU05750

Phenotypes of a mutant

  • severe growth phenotype associated with a broadly disturbed iron homeostasis PubMed

Database entries

  • DBTBS entry: no entry
  • SubtiList entry: [1]

Additional information

The protein

Basic information/ Evolution

  • Catalyzed reaction/ biological activity: transfers iron onto the B. subtilis SUF system (SufU-SufS) for iron-sulfur cluster biosynthesis PubMed
  • Protein family:
  • Paralogous protein(s):

Extended information on the protein

  • Kinetic information:
  • Domains:
  • Modification:
  • Cofactor(s): Fe(2+) is bound with high affinity PubMed
  • Effectors of protein activity:

Database entries

  • KEGG entry: [2]
  • E.C. number:

Additional information

Expression and regulation

  • Operon:
  • Sigma factor:
  • Regulation:
  • Regulatory mechanism:
  • Additional information:

Biological materials

  • Expression vector:
  • lacZ fusion:
  • GFP fusion:
  • two-hybrid system:
  • Antibody:

Labs working on this gene/protein

Your additional remarks

References

Additional publications: PubMed