Difference between revisions of "SwrAA/1"

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|style="background:#ABCDEF;" align="center"|'''Function''' || control of [[DegU]] activity
 
|style="background:#ABCDEF;" align="center"|'''Function''' || control of [[DegU]] activity
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|colspan="2" style="background:#FAF8CC;" align="center"| '''Gene expression levels in [http://cellpublisher.gobics.de/subtiexpress/ ''Subti''Express]''': [http://cellpublisher.gobics.de/subtiexpress/bsu/BSU35230 swrAA/1]
 
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|colspan="2" style="background:#FAF8CC;" align="center"| '''Interactions involving this protein in [http://cellpublisher.gobics.de/subtinteract/startpage/start/ ''Subt''Interact]''': [http://cellpublisher.gobics.de/subtinteract/interactionList/2/SwrA SwrA]
 
|colspan="2" style="background:#FAF8CC;" align="center"| '''Interactions involving this protein in [http://cellpublisher.gobics.de/subtinteract/startpage/start/ ''Subt''Interact]''': [http://cellpublisher.gobics.de/subtinteract/interactionList/2/SwrA SwrA]

Revision as of 16:28, 7 August 2012

  • Description: control of DegU activity, enhances sigD transcription, inactive pseudogene in strain 168

Gene name swrA
Synonyms yvzD, swrAA, ifm
Essential no
Product swarming motility protein
Function control of DegU activity
Gene expression levels in SubtiExpress: swrAA/1
Interactions involving this protein in SubtInteract: SwrA
MW, pI - , -
Gene length, protein length 336 bp, -
Immediate neighbours minJ, swrAA/2
Gene sequence (+200bp) Protein sequence
Genetic context
YvzD context.gif
This image was kindly provided by SubtiList
Expression at a glance   PubMed
1 expression.png
























Categories containing this gene/protein

biofilm formation, motility and chemotaxis, transcription factors and their control, pseudogenes

This gene is a member of the following regulons

The gene

Basic information

  • Locus tag: BSU35230

Phenotypes of a mutant

Database entries

  • DBTBS entry: no entry
  • SubtiList entry: [1]

Additional information

  • This protein is functional in undomesticated strains of B.subtilis but not in laboratory strains, such as 168, because of a frameshift mutation. Therefore laboratory strains of B.subtilis are unable to swarm.
  • The frameshift in strain 168 is caused by a single insertion of an adenine in the codon for Tyr-12 which leads to the premature truncation of the protein in residue 13. In addition, the C-terminal section of swrAA was predicted to be an ORF (yvzD) by the genome project.
  • Correction of sfp, epsC, swrAA, and degQ as well as introduction of rapP from a plasmid present in NCIB3610 results in biofilm formation in B. subtilis 168 PubMed


The protein

Basic information/ Evolution

  • Catalyzed reaction/ biological activity:
    • interacts with the N-terminal domain of DegU to control the activity of DegU PubMed
  • Protein family:
  • Paralogous protein(s):

Extended information on the protein

  • Kinetic information:
  • Domains:
  • Modification:
  • Cofactor(s):
  • Effectors of protein activity:

Database entries

  • Structure:
  • KEGG entry: [2]
  • E.C. number:

Additional information

Expression and regulation

  • Regulation:
  • Regulatory mechanism:
  • Additional information:

Biological materials

  • Mutant:
  • Expression vector:
  • lacZ fusion:
  • GFP fusion:
  • two-hybrid system:
  • Antibody:

Labs working on this gene/protein

Your additional remarks

References

Reviews


Original publications

Additional publications: PubMed