YvmC

• Description: cyclodipeptide synthase
  
  

Gene name	yvmC
Synonyms
Essential	no
Product	cyclodipeptide synthase
Function	biosynthesis of the extracellular iron chelate pulcherrimin
Gene expression levels in SubtiExpress: yvmC
MW, pI	28 kDa, 6.612
Gene length, protein length	744 bp, 248 aa
Immediate neighbours	cypX, yvmB
Get the DNA and protein sequences (Barbe et al., 2009)
Genetic context This image was kindly provided by SubtiList
Expression at a glance   PubMed

Categories containing this gene/protein

acquisition of iron, iron metabolism

This gene is a member of the following regulons

AbrB regulon

The gene

Basic information

• Locus tag: BSU35070

Database entries

• DBTBS entry: no entry

• SubtiList entry: [1]

The protein

Basic information/ Evolution

• Catalyzed reaction/ biological activity:
  • synthesis of the cyclic dipeptide cyclo-L-leucyl-L-leucyl with the corresponding charged tRNAs as substrates in an ATP-dependent manner PubMed

• Protein family:

• Paralogous protein(s):

Extended information on the protein

• Kinetic information:

• Domains:

• Modification:

• Cofactor(s):

• Effectors of protein activity:

• Interactions:

• Localization:

Database entries

• Structure: 3S7T (from B. licheniformis, 70% identity, 86% similarity) PubMed

• UniProt: O34351

• KEGG entry: [2]

• E.C. number:

Expression and regulation

• Operon: yvmC-cypX Reference

• Expression browser: yvmC PubMed

• Sigma factor:

• Regulation:

• Regulatory mechanism:
  • AbrB: transcription repression PubMed

• Additional information:

Biological materials

• Mutant:

• Expression vector:

• lacZ fusion:

• GFP fusion:

• two-hybrid system:

• Antibody:

References

Additional publications: PubMed

additional paper