Difference between revisions of "DegQ"

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|style="background:#ABCDEF;" align="center"|'''Function''' || regulation of exoenzyme synthesis
 
|style="background:#ABCDEF;" align="center"|'''Function''' || regulation of exoenzyme synthesis
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|colspan="2" style="background:#FAF8CC;" align="center"| '''Gene expression levels in [http://cellpublisher.gobics.de/subtiexpress/ ''Subti''Express]''': [http://cellpublisher.gobics.de/subtiexpress/bsu/BSU31720 degQ]
 
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|colspan="2" style="background:#FAF8CC;" align="center"| '''Interactions involving this protein in [http://cellpublisher.gobics.de/subtinteract/startpage/start/ ''Subt''Interact]''': [http://cellpublisher.gobics.de/subtinteract/interactionList/2/DegQ DegQ]
 
|colspan="2" style="background:#FAF8CC;" align="center"| '''Interactions involving this protein in [http://cellpublisher.gobics.de/subtinteract/startpage/start/ ''Subt''Interact]''': [http://cellpublisher.gobics.de/subtinteract/interactionList/2/DegQ DegQ]

Revision as of 15:30, 7 August 2012

  • Description: stimulates production of degradative enzymes and of extracellular poly-gamma-glutamate PubMed, stimulates phosphorylation of DegU by DegS PubMed, gene is not expressed in the lab strain 168 due to promoter down mutation in the -10 region (T - 10 ---> C) PubMed

Gene name degQ
Synonyms sacQ
Essential no
Product pleiotropic regulator
Function regulation of exoenzyme synthesis
Gene expression levels in SubtiExpress: degQ
Interactions involving this protein in SubtInteract: DegQ
MW, pI 5 kDa, 6.536
Gene length, protein length 138 bp, 46 aa
Immediate neighbours comQ, yuzC
Get the DNA and protein sequences
(Barbe et al., 2009)
Genetic context
DegQ context.gif
This image was kindly provided by SubtiList
Expression at a glance   PubMed
DegQ expression.png
























Categories containing this gene/protein

biofilm formation, transcription factors and their control

This gene is a member of the following regulons

ComA regulon, DegU regulon

The gene

Basic information

  • Locus tag: BSU31720

Phenotypes of a mutant

loss of poly-gamma-glutamate production PubMed, no synthesis of nonribosomal peptides iturin A and plipastatin PubMed1 PubMed2, reduced synthesis of degradative enzymes PubMed, increased genetic competence PubMed

Database entries

  • DBTBS entry: [1]
  • SubtiList entry: [2]

Additional information

  • Correction of sfp, epsC, swrAA, and degQ as well as introduction of rapP from a plasmid present in NCIB3610 results in biofilm formation in B. subtilis 168 PubMed

The protein

Basic information/ Evolution

  • Catalyzed reaction/ biological activity:
  • Protein family: degQ family (according to Swiss-Prot)
  • Paralogous protein(s):

Extended information on the protein

  • Kinetic information:
  • Domains:
  • Modification:
  • Cofactor(s):
  • Effectors of protein activity:

Database entries

  • Structure:
  • KEGG entry: [3]
  • E.C. number:

Additional information

Expression and regulation

  • Additional information: the gene is not expressed in the lab strain 168 due to promoter down mutation in the -10 region (T - 10 ---> C) PubMed

Biological materials

  • Mutant: QB4851 (cat), available in the Stülke lab
  • Expression vector:
  • lacZ fusion:
  • GFP fusion:
  • two-hybrid system:
  • Antibody:

Labs working on this gene/protein

Your additional remarks

References

Additional publications: PubMed