Difference between revisions of "SpoIIE"

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* '''Description:''' [[Protein kinases and phosphatases|protein serine phosphatase]], septum-associated PP2C, dephosphorylation of [[SpoIIAA]] <br/><br/>
  
 
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|style="background:#ABCDEF;" align="center"|'''Function''' || control of [[SigF]] activity <br/>required for normal formation of the asymmetric septum
 
|style="background:#ABCDEF;" align="center"|'''Function''' || control of [[SigF]] activity <br/>required for normal formation of the asymmetric septum
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|colspan="2" style="background:#FAF8CC;" align="center"| '''Gene expression levels in [http://cellpublisher.gobics.de/subtiexpress/ ''Subti''Express]''': [http://cellpublisher.gobics.de/subtiexpress/bsu/BSU00640 spoIIE]
 
 
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|colspan="2" style="background:#FAF8CC;" align="center"| '''Interactions involving this protein in [http://cellpublisher.gobics.de/subtinteract/startpage/start/ ''Subt''Interact]''': [http://cellpublisher.gobics.de/subtinteract/interactionList/2/SpoIIE SpoIIE]
 
|colspan="2" style="background:#FAF8CC;" align="center"| '''Interactions involving this protein in [http://cellpublisher.gobics.de/subtinteract/startpage/start/ ''Subt''Interact]''': [http://cellpublisher.gobics.de/subtinteract/interactionList/2/SpoIIE SpoIIE]
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|colspan="2" | '''Genetic context''' <br/> [[Image:spoIIE_context.gif]]
 
|colspan="2" | '''Genetic context''' <br/> [[Image:spoIIE_context.gif]]
 
  <div align="right"> <small>This image was kindly provided by [http://genolist.pasteur.fr/SubtiList/ SubtiList]</small></div>
 
  <div align="right"> <small>This image was kindly provided by [http://genolist.pasteur.fr/SubtiList/ SubtiList]</small></div>
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|colspan="2" |'''[http://genome.jouy.inra.fr/cgi-bin/seb/viewdetail.py?id=spoIIE_70538_73021_1 Expression at a glance]'''&#160;&#160;&#160;{{PubMed|22383849}}<br/>[[Image:spoIIE_expression.png|500px]]
 
 
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* '''Operon:''' ''spoIIE'' (DBTBS)
 
* '''Operon:''' ''spoIIE'' (DBTBS)
  
* '''Expression browser:''' [http://genome.jouy.inra.fr/cgi-bin/seb/viewdetail.py?id=spoIIE_70538_73021_1 spoIIE] {{PubMed|22383849}}
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* '''[[Sigma factor]]:''' [[SigA]] [http://www.ncbi.nlm.nih.gov/sites/entrez/1556084 PubMed]
 
 
* '''Sigma factor:''' [[SigA]] [http://www.ncbi.nlm.nih.gov/sites/entrez/1556084 PubMed]
 
  
 
* '''Regulation:'''  
 
* '''Regulation:'''  

Revision as of 10:20, 7 August 2012

Gene name spoIIE
Synonyms spoIIH, spoIIK
Essential no
Product protein serine phosphatase, septum-associated PP2C
Function control of SigF activity
required for normal formation of the asymmetric septum
Interactions involving this protein in SubtInteract: SpoIIE
Metabolic function and regulation of this protein in SubtiPathways:
Stress
MW, pI 91 kDa, 6.137
Gene length, protein length 2481 bp, 827 aa
Immediate neighbours trnSL-Glu1, yabS
Get the DNA and protein sequences
(Barbe et al., 2009)
Genetic context
SpoIIE context.gif
This image was kindly provided by SubtiList







Categories containing this gene/protein

protein modification, sigma factors and their control, membrane proteins

This gene is a member of the following regulons

Spo0A regulon

The gene

Basic information

  • Locus tag: BSU00640

Phenotypes of a mutant

Database entries

  • DBTBS entry: [1]
  • SubtiList entry: [2]

Additional information

The protein

Basic information/ Evolution

  • Catalyzed reaction/ biological activity: dephosphorylation of SpoIIAA
  • Paralogous protein(s):

Extended information on the protein

  • Kinetic information:
  • Domains:
  • Modification:
  • Cofactor(s):
  • Effectors of protein activity:
  • Localization:
    • cell membrane (according to Swiss-Prot)
    • localizes to the polar cell division sites where it causes FtsZ to relocate from mid-cell to form polar Z-rings

Database entries

  • KEGG entry: [3]

Additional information

Expression and regulation

  • Operon: spoIIE (DBTBS)
  • Regulation:
    • expressed under conditions that trigger sporulation (Spo0A) PubMed
  • Regulatory mechanism:
  • Additional information:

Biological materials

  • Mutant:
  • Expression vector:
  • lacZ fusion:
  • GFP fusion:
  • two-hybrid system:
  • Antibody:

Labs working on this gene/protein

Imrich Barak, Slovak Academy of Science, Bratislava, Slovakia homepage

Your additional remarks

References

Additional publications: PubMed