YfjR

• Description: similar to 3-hydroxyisobutyrate dehydrogenase
  
  

Gene name	yfjR
Synonyms
Essential	no
Product	3-hydroxyisobutyrate dehydrogenase
Function	unknown
MW, pI	27 kDa, 4.782
Gene length, protein length	783 bp, 261 aa
Immediate neighbours	pdaA, yfjQ
Get the DNA and protein sequences (Barbe et al., 2009)
Genetic context This image was kindly provided by SubtiList

Categories containing this gene/protein

phosphoproteins, poorly characterized/ putative enzymes

This gene is a member of the following regulons

YclJ regulon

The gene

Basic information

• Locus tag: BSU07990

Database entries

• DBTBS entry: [1]

• SubtiList entry: [2]

The protein

Basic information/ Evolution

• Catalyzed reaction/ biological activity:

• Protein family: 3-hydroxyisobutyrate dehydrogenase family (according to Swiss-Prot)

• Paralogous protein(s): YkwC

Extended information on the protein

• Kinetic information:

• Domains:

• Modification: phosphorylated on ser/ thr/ tyr PubMed

• Cofactor(s):

• Effectors of protein activity:

• Interactions:

• Localization:

Database entries

• Structure:

• UniProt: O34969

• KEGG entry: [3]

• E.C. number:

Expression and regulation

• Operon: yfjR (according to DBTBS)

• Expression browser: yfjR PubMed

• Sigma factor:

• Regulation:

• Regulatory mechanism:
  • YclJ: transcription activation PubMed

• Additional information:

Biological materials

• Mutant:

• Expression vector:

• lacZ fusion:

• GFP fusion:

• two-hybrid system:

• Antibody:

References

Mitsuo Ogura, Kensuke Tsukahara, Teruo Tanaka
Identification of the sequences recognized by the Bacillus subtilis response regulator YclJ.
Arch Microbiol: 2010, 192(7);569-80
[PubMed:20512483] [WorldCat.org] [DOI] (I p)

Alain Lévine, Françoise Vannier, Cédric Absalon, Lauriane Kuhn, Peter Jackson, Elaine Scrivener, Valérie Labas, Joëlle Vinh, Patrick Courtney, Jérôme Garin, Simone J Séror
Analysis of the dynamic Bacillus subtilis Ser/Thr/Tyr phosphoproteome implicated in a wide variety of cellular processes.
Proteomics: 2006, 6(7);2157-73
[PubMed:16493705] [WorldCat.org] [DOI] (P p)