Difference between revisions of "DctP"

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m (Reverted edits by 134.76.70.252 (talk) to last revision by Jstuelk)
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= This gene is a member of the following [[regulons]] =
 
= This gene is a member of the following [[regulons]] =
{{SubtiWiki regulon|[[CcpA regulon]]}}
+
{{SubtiWiki regulon|[[CcpA regulon]]}},
 +
{{SubtiWiki regulon|[[FsrA regulon]]}}
  
 
=The gene=
 
=The gene=
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=== Additional information===
 
=== Additional information===
 
 
  
  
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** ''[[dctP]]'': [[SigA]] {{PubMed|10708364}}
 
** ''[[dctP]]'': [[SigA]] {{PubMed|10708364}}
  
* '''Regulation:''' repressed by glucose (6.2-fold) ([[CcpA]]) {{PubMed|12850135}}   
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* '''Regulation:'''  
 +
** repressed by glucose (6.2-fold) ([[CcpA]]) {{PubMed|12850135}}   
 +
** part of the iron sparing response ([[FsrA]]) {{PubMed|22389480}}
  
* '''Regulatory mechanism:''' [[CcpA]]: transcription repression {{PubMed|12850135}}
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* '''Regulatory mechanism:'''  
 +
** [[CcpA]]: transcription repression {{PubMed|12850135}}
 +
** [[FsrA]]: translation inhibition {{PubMed|22389480}}
  
 
* '''Additional information:'''  
 
* '''Additional information:'''  
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=References=
 
=References=
  
<pubmed>12850135, 10708364 10627041, 12949159 20363944 </pubmed>
+
<pubmed>12850135, 10708364 10627041, 12949159 20363944 22389480</pubmed>
  
 
[[Category:Protein-coding genes]]
 
[[Category:Protein-coding genes]]

Revision as of 17:59, 14 March 2012

  • Description: uptake of succinate, fumurate, malate and oxaloacetate via proton symport

Gene name dctP
Synonyms ydbH, dctA
Essential no
Product C4-dicarboxylate transport protein
Function uptake of succinate, fumurate, malate and oxaloacetate
Metabolic function and regulation of this protein in SubtiPathways:
Central C-metabolism
MW, pI 45 kDa, 8.668
Gene length, protein length 1263 bp, 421 aa
Immediate neighbours dctR, ydbI
Get the DNA and protein sequences
(Barbe et al., 2009)
Genetic context
DctP context.gif
This image was kindly provided by SubtiList







Categories containing this gene/protein

transporters/ other, utilization of specific carbon sources, membrane proteins

This gene is a member of the following regulons

CcpA regulon, FsrA regulon

The gene

Basic information

  • Locus tag: BSU04470

Phenotypes of a mutant

Database entries

  • DBTBS entry: no entry
  • SubtiList entry: [1]

Additional information

The protein

Basic information/ Evolution

  • Catalyzed reaction/ biological activity: uptake of succinate, fumurate, malate and oxaloacetate via proton symport PubMed
  • Protein family: View classification (according to Swiss-Prot)

Extended information on the protein

  • Kinetic information:
  • Domains:
  • Modification:
  • Cofactor(s):
  • Effectors of protein activity:

Database entries

  • Structure:
  • KEGG entry: [2]
  • E.C. number:

Additional information

Expression and regulation

  • Regulation:
  • Additional information:

Biological materials

  • Mutant:
  • Expression vector:
  • lacZ fusion:
  • GFP fusion:
  • two-hybrid system:
  • Antibody:

Labs working on this gene/protein

Your additional remarks

References