Difference between revisions of "PlsX"

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* '''Locus tag:''' BSU15890
 
* '''Locus tag:''' BSU15890
 
[http://genome.jouy.inra.fr/cgi-bin/seb/viewdetail.py?id=plsX_1662547_1663548_1 Expression]
 
  
 
===Phenotypes of a mutant ===
 
===Phenotypes of a mutant ===

Revision as of 09:16, 28 January 2012

  • Description: acyl-acyl carrier protein (ACP):phosphate acyltransferase, catalyzes the synthesis of the intermediate fatty acyl-phosphate (acyl-PO4)

Gene name plsX
Synonyms ylpD
Essential yes PubMed
Product acyl-acyl carrier protein (ACP):phosphate acyltransferase
Function biosynthesis of phospholipids
Interactions involving this protein in SubtInteract: PlsX
Metabolic function and regulation of this protein in SubtiPathways:
Lipid synthesis
MW, pI 35 kDa, 5.492
Gene length, protein length 999 bp, 333 aa
Immediate neighbours fapR, fabD
Get the DNA and protein sequences
(Barbe et al., 2009)
Genetic context
PlsX context.gif
This image was kindly provided by SubtiList







Categories containing this gene/protein

biosynthesis of lipids, essential genes

This gene is a member of the following regulons

ComA regulon, FapR regulon

The gene

Basic information

  • Locus tag: BSU15890

Phenotypes of a mutant

Database entries

  • DBTBS entry: [1]
  • SubtiList entry: [2]

Additional information

The protein

Basic information/ Evolution

  • Catalyzed reaction/ biological activity: catalyzes the synthesis of the intermediate fatty acyl-phosphate (acyl-PO4)
  • Protein family: plsX family (according to Swiss-Prot)
  • Paralogous protein(s):

Extended information on the protein

  • Kinetic information:
  • Domains:
  • Modification:
  • Cofactor(s):
  • Effectors of protein activity:

Database entries

  • KEGG entry: [3]
  • E.C. number:

Additional information

Expression and regulation

  • Regulation:
    • induced if the cells experience an accumulation of malonyl-CoA (FapR) PubMed
    • expressed at high cell density (ComA) PubMed
    • induced upon fatty acid biosynthesis inhibition PubMed
  • Additional information:

Biological materials

  • Mutant:
  • Expression vector:
  • lacZ fusion:
  • GFP fusion:
  • two-hybrid system: B. pertussis adenylate cyclase-based bacterial two hybrid system (BACTH), available in Matsumoto lab PubMed
  • Antibody:

Labs working on this gene/protein

Your additional remarks

References

Additional publications: PubMed