Difference between revisions of "ImmR"

From SubtiWiki
Jump to: navigation, search
m (Reverted edits by 134.76.70.252 (talk) to last revision by Jstuelk)
Line 57: Line 57:
 
=== Additional information===
 
=== Additional information===
  
[http://genome.jouy.inra.fr/cgi-bin/seb/viewdetail.py?id=immR_531130_531513_-1 Expression]
+
 
 +
 
  
 
=The protein=
 
=The protein=

Revision as of 19:47, 27 January 2012

  • Description: transcriptional repressor, controls expression of genes of the mobile genetic element ICEBs1, induction by the SOS response or the RapI-PhrI sensory system

Gene name immR
Synonyms ydcN
Essential no
Product transcriptional regulator (phage-related) (Xre family)
Function control of transfer of the mobile
genetic element ICEBs1
Interactions involving this protein in SubtInteract: ImmR
MW, pI 14 kDa, 4.989
Gene length, protein length 381 bp, 127 aa
Immediate neighbours immA, xis
Get the DNA and protein sequences
(Barbe et al., 2009)
Genetic context
YdcN context.gif
This image was kindly provided by SubtiList



Categories containing this gene/protein

transcription factors and their control, mobile genetic elements

This gene is a member of the following regulons

The ImmR regulon:

The gene

Basic information

  • Locus tag: BSU04820

Phenotypes of a mutant

Database entries

  • DBTBS entry: no entry
  • SubtiList entry: [1]

Additional information

The protein

Basic information/ Evolution

  • Catalyzed reaction/ biological activity:
  • Protein family:
  • Paralogous protein(s):

Extended information on the protein

  • Kinetic information:
  • Domains:
  • Modification:
  • Cofactor(s):
  • Effectors of protein activity: binding of RapI to ImmR results in loss of DNA-binding activity of ImmR and subsequently in induction of ImmR-repressed genes PubMed

Database entries

  • Structure:
  • KEGG entry: [2]
  • E.C. number:

Additional information

Expression and regulation

  • Operon:
  • Regulation:
  • Regulatory mechanism:
  • Additional information: ImmR is degraded by the anti-repressor ImmA PubMed

Biological materials

  • Mutant:
  • Expression vector:
  • lacZ fusion:
  • GFP fusion:
  • two-hybrid system:
  • Antibody:

Labs working on this gene/protein

Your additional remarks

References

Baundauna Bose, Alan D Grossman
Regulation of horizontal gene transfer in Bacillus subtilis by activation of a conserved site-specific protease.
J Bacteriol: 2011, 193(1);22-9
[PubMed:21036995] [WorldCat.org] [DOI] (I p)

Baundauna Bose, Jennifer M Auchtung, Catherine A Lee, Alan D Grossman
A conserved anti-repressor controls horizontal gene transfer by proteolysis.
Mol Microbiol: 2008, 70(3);570-82
[PubMed:18761623] [WorldCat.org] [DOI] (I p)

Jennifer M Auchtung, Catherine A Lee, Katherine L Garrison, Alan D Grossman
Identification and characterization of the immunity repressor (ImmR) that controls the mobile genetic element ICEBs1 of Bacillus subtilis.
Mol Microbiol: 2007, 64(6);1515-28
[PubMed:17511812] [WorldCat.org] [DOI] (P p)