Difference between revisions of "TenI"
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* '''Locus tag:''' BSU11660 | * '''Locus tag:''' BSU11660 | ||
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+ | [http://genome.jouy.inra.fr/cgi-bin/seb/viewdetail.py?id=tenI_1243134_1243751_1 Expression] | ||
===Phenotypes of a mutant === | ===Phenotypes of a mutant === |
Revision as of 16:44, 24 January 2012
- Description: transcriptional activator of extracellular enzyme genes
Gene name | tenI |
Synonyms | |
Essential | no |
Product | transcriptional activator |
Function | regulation of extracellular enzyme genes |
Metabolic function and regulation of this protein in SubtiPathways: Thiamin | |
MW, pI | 22 kDa, 8.132 |
Gene length, protein length | 615 bp, 205 aa |
Immediate neighbours | tenA, thiO |
Get the DNA and protein sequences (Barbe et al., 2009) | |
Genetic context This image was kindly provided by SubtiList
|
Contents
Categories containing this gene/protein
biosynthesis of cofactors, transcription factors and their control
This gene is a member of the following regulons
The gene
Basic information
- Locus tag: BSU11660
Phenotypes of a mutant
Database entries
- DBTBS entry: [1]
- SubtiList entry: [2]
Additional information
The protein
Basic information/ Evolution
- Catalyzed reaction/ biological activity:
- Protein family: TMP-PPase family (according to Swiss-Prot)
- Paralogous protein(s): ThiE
Extended information on the protein
- Kinetic information:
- Domains:
- Modification:
- Cofactor(s):
- Effectors of protein activity:
Database entries
- Structure: 1YAD
- UniProt: P25053
- KEGG entry: [3]
- E.C. number:
Additional information
Expression and regulation
- Regulatory mechanism:
- Additional information:
Biological materials
- Mutant:
- Expression vector:
- lacZ fusion:
- GFP fusion:
- two-hybrid system:
- Antibody:
Labs working on this gene/protein
Your additional remarks
References
Reviews
T P Begley, D M Downs, S E Ealick, F W McLafferty, A P Van Loon, S Taylor, N Campobasso, H J Chiu, C Kinsland, J J Reddick, J Xi
Thiamin biosynthesis in prokaryotes.
Arch Microbiol: 1999, 171(5);293-300
[PubMed:10382260]
[WorldCat.org]
[DOI]
(P p)
Original publications
Angela V Toms, Amy L Haas, Joo-Heon Park, Tadhg P Begley, Steven E Ealick
Structural characterization of the regulatory proteins TenA and TenI from Bacillus subtilis and identification of TenA as a thiaminase II.
Biochemistry: 2005, 44(7);2319-29
[PubMed:15709744]
[WorldCat.org]
[DOI]
(P p)
A S Pang, S Nathoo, S L Wong
Cloning and characterization of a pair of novel genes that regulate production of extracellular enzymes in Bacillus subtilis.
J Bacteriol: 1991, 173(1);46-54
[PubMed:1898926]
[WorldCat.org]
[DOI]
(P p)