YueB

• Description: receptor for phage SPPI
  
  

Gene name	yueB
Synonyms
Essential	no
Product	receptor for phage SPPI
Function	unknown
MW, pI	119 kDa, 4.302
Gene length, protein length	3228 bp, 1076 aa
Immediate neighbours	yueC, yukB
Get the DNA and protein sequences (Barbe et al., 2009)
Genetic context This image was kindly provided by SubtiList

Categories containing this gene/protein

phage-related functions, membrane proteins

The gene

Basic information

• Locus tag: BSU31860

Phenotypes of a mutant

• resistance to phage SPPI PubMed

Database entries

• DBTBS entry: no entry

• SubtiList entry: [1]

The protein

Basic information/ Evolution

• Catalyzed reaction/ biological activity:
  • receptor for phage SPP1 PubMed
  • required for depolarization of the cytoplasmic membrane upon binding of phage SPP1 PubMed

• Protein family:

• Paralogous protein(s):

Extended information on the protein

• Kinetic information:

• Domains:

• Modification:

• Cofactor(s):

• Effectors of protein activity:

• Interactions:
  • YueB is a member of a suspected group of hubs proteins that were suggested to be involved in a large number of interactions PubMed

• Localization:
  • cell membrane PubMed, localizes preferentially to the cell poles PubMed
  • exposed to the surface PubMed
  • cytoplasm (homogeneous) PubMed

Database entries

• Structure:

• UniProt: O32101

• KEGG entry: [2]

• E.C. number:

Expression and regulation

• Operon: yukE-yukD-yukC-yukB-yueB PubMed

• Sigma factor:

• Regulation:

• Regulatory mechanism:

• Additional information:

Biological materials

• Mutant:

• Expression vector:

• lacZ fusion:

• GFP fusion:

• two-hybrid system:

• Antibody:

References

Additional publications: PubMed

Inês Vinga, Catarina Baptista, Isabelle Auzat, Isabelle Petipas, Rudi Lurz, Paulo Tavares, Mário A Santos, Carlos São-José
Role of bacteriophage SPP1 tail spike protein gp21 on host cell receptor binding and trigger of phage DNA ejection.
Mol Microbiol: 2012, 83(2);289-303
[PubMed:22171743] [WorldCat.org] [DOI] (I p)

Elodie Marchadier, Rut Carballido-López, Sophie Brinster, Céline Fabret, Peggy Mervelet, Philippe Bessières, Marie-Françoise Noirot-Gros, Vincent Fromion, Philippe Noirot
An expanded protein-protein interaction network in Bacillus subtilis reveals a group of hubs: Exploration by an integrative approach.
Proteomics: 2011, 11(15);2981-91
[PubMed:21630458] [WorldCat.org] [DOI] (I p)

Catarina Baptista, Mário A Santos, Carlos São-José
Phage SPP1 reversible adsorption to Bacillus subtilis cell wall teichoic acids accelerates virus recognition of membrane receptor YueB.
J Bacteriol: 2008, 190(14);4989-96
[PubMed:18487323] [WorldCat.org] [DOI] (I p)

Celia Plisson, Helen E White, Isabelle Auzat, Amineh Zafarani, Carlos São-José, Sophie Lhuillier, Paulo Tavares, Elena V Orlova
Structure of bacteriophage SPP1 tail reveals trigger for DNA ejection.
EMBO J: 2007, 26(15);3720-8
[PubMed:17611601] [WorldCat.org] [DOI] (P p)

Carlos São-José, Sophie Lhuillier, Rudi Lurz, Ronald Melki, Jean Lepault, Mário Almeida Santos, Paulo Tavares
The ectodomain of the viral receptor YueB forms a fiber that triggers ejection of bacteriophage SPP1 DNA.
J Biol Chem: 2006, 281(17);11464-70
[PubMed:16481324] [WorldCat.org] [DOI] (P p)

Jean-Christophe Meile, Ling Juan Wu, S Dusko Ehrlich, Jeff Errington, Philippe Noirot
Systematic localisation of proteins fused to the green fluorescent protein in Bacillus subtilis: identification of new proteins at the DNA replication factory.
Proteomics: 2006, 6(7);2135-46
[PubMed:16479537] [WorldCat.org] [DOI] (P p)

Carlos São-José, Catarina Baptista, Mário A Santos
Bacillus subtilis operon encoding a membrane receptor for bacteriophage SPP1.
J Bacteriol: 2004, 186(24);8337-46
[PubMed:15576783] [WorldCat.org] [DOI] (P p)