Difference between revisions of "ComGC"
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| − | * '''Description:''' DNA uptake, major component of the pseudopilus <br/><br/> | + | * '''Description:''' DNA uptake, major component of the [[pseudopilus]] <br/><br/> |
{| align="right" border="1" cellpadding="2" | {| align="right" border="1" cellpadding="2" | ||
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|style="background:#ABCDEF;" align="center"| '''Essential''' || no | |style="background:#ABCDEF;" align="center"| '''Essential''' || no | ||
|- | |- | ||
| − | |style="background:#ABCDEF;" align="center"| '''Product''' || major | + | |style="background:#ABCDEF;" align="center"| '''Product''' || major pseudopilin |
|- | |- | ||
|style="background:#ABCDEF;" align="center"|'''Function''' || [[genetic competence]] | |style="background:#ABCDEF;" align="center"|'''Function''' || [[genetic competence]] | ||
| Line 55: | Line 55: | ||
=== Additional information=== | === Additional information=== | ||
| − | |||
| − | |||
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=The protein= | =The protein= | ||
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* '''Interactions:''' | * '''Interactions:''' | ||
| − | ** forms large complexes (the pseudopilus) {{PubMed|21278288}} | + | ** [[ComGB]]-[[ComGC]] {{PubMed|15083159}} |
| + | ** forms large complexes (the [[pseudopilus]]) {{PubMed|21278288}} | ||
* '''Localization:''' | * '''Localization:''' | ||
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=References= | =References= | ||
| − | + | ==Reviews== | |
| + | <pubmed> 15083159 </pubmed> | ||
| + | ==Original publications== | ||
<pubmed>11744713,11814663,9422590,16751195,9723928,1968455,7783624,21278288,12107147, 2507524 8196543</pubmed> | <pubmed>11744713,11814663,9422590,16751195,9723928,1968455,7783624,21278288,12107147, 2507524 8196543</pubmed> | ||
[[Category:Protein-coding genes]] | [[Category:Protein-coding genes]] | ||
Revision as of 15:04, 8 April 2011
- Description: DNA uptake, major component of the pseudopilus
| Gene name | comGC |
| Synonyms | |
| Essential | no |
| Product | major pseudopilin |
| Function | genetic competence |
| Metabolic function and regulation of this protein in SubtiPathways: Protein secretion | |
| MW, pI | 10 kDa, 6.325 |
| Gene length, protein length | 294 bp, 98 aa |
| Immediate neighbours | comGD, comGB |
| Get the DNA and protein sequences (Barbe et al., 2009) | |
Genetic context 
This image was kindly provided by SubtiList
| |
Contents
Categories containing this gene/protein
genetic competence, membrane proteins
This gene is a member of the following regulons
The gene
Basic information
- Locus tag: BSU24710
Phenotypes of a mutant
Database entries
- DBTBS entry: [1]
- SubtiList entry: [2]
Additional information
The protein
Basic information/ Evolution
- Catalyzed reaction/ biological activity:
- Protein family: comGC family (according to Swiss-Prot)
- Paralogous protein(s):
Extended information on the protein
- Kinetic information:
- Domains:
- Modification:
- Cofactor(s):
=
- Effectors of protein activity:
- Interactions:
- ComGB-ComGC PubMed
- forms large complexes (the pseudopilus) PubMed
- Localization:
= Database entries
- Structure:
- UniProt: P25955
- KEGG entry: [3]
- E.C. number:
Additional information
Expression and regulation
- Regulation:
- repressed by casamino acids PubMed
- Additional information:
Biological materials
- Mutant:
- Expression vector:
- lacZ fusion:
- GFP fusion:
- two-hybrid system:
- Antibody:
Labs working on this gene/protein
Your additional remarks
References
Reviews
Inês Chen, David Dubnau
DNA uptake during bacterial transformation.
Nat Rev Microbiol: 2004, 2(3);241-9
[PubMed:15083159]
[WorldCat.org]
[DOI]
(P p)
Original publications
