AldY

• Description: aldehyde dehydrogenase (NAD), general stress protein
  
  

Gene name	aldY
Synonyms	yxkE
Essential	no
Product	aldehyde dehydrogenase (NAD)
Function	stress resistance
MW, pI	52 kDa, 5.021
Gene length, protein length	1455 bp, 485 aa
Immediate neighbours	yxkF, yxkD
Get the DNA and protein sequences (Barbe et al., 2009)
Genetic context This image was kindly provided by SubtiList

The gene

Basic information

• Locus tag: BSU38830

Database entries

• DBTBS entry: [1]

• SubtiList entry: [2]

Categories containing this gene/protein

general stress proteins (controlled by SigB), poorly characterized/ putative enzymes

The protein

Basic information/ Evolution

• Catalyzed reaction/ biological activity:

• Protein family: aldehyde dehydrogenase family (according to Swiss-Prot)

• Paralogous protein(s):

Extended information on the protein

• Kinetic information:

• Domains:

• Modification:

• Cofactor(s):

• Effectors of protein activity:

• Interactions:

• Localization:

Database entries

• Structure:

• UniProt: P94358

• KEGG entry: [3]

• E.C. number:

Expression and regulation

• Operon: aldY PubMed

• Sigma factor: SigB PubMed

• Regulation:
  • induced by stress (SigB) PubMed

• Regulatory mechanism:

• Additional information:

Biological materials

• Mutant:

• Expression vector:

• lacZ fusion:

• GFP fusion:

• two-hybrid system:

• Antibody:

References

Dirk Höper, Uwe Völker, Michael Hecker
Comprehensive characterization of the contribution of individual SigB-dependent general stress genes to stress resistance of Bacillus subtilis.
J Bacteriol: 2005, 187(8);2810-26
[PubMed:15805528] [WorldCat.org] [DOI] (P p)

A Petersohn, J Bernhardt, U Gerth, D Höper, T Koburger, U Völker, M Hecker
Identification of sigma(B)-dependent genes in Bacillus subtilis using a promoter consensus-directed search and oligonucleotide hybridization.
J Bacteriol: 1999, 181(18);5718-24
[PubMed:10482513] [WorldCat.org] [DOI] (P p)